Low plasma vitamin A concentration is associated with tuberculosis in Moroccan population: a preliminary case control study

Vitamin A plays numerous roles in immune system. Its deficiency alters both the innate and adaptive immunity. Previous results reported that the micronutrients deficiency, particularly vitamin A, is observed in patients with tuberculosis. Thus, we aimed in this study to assess vitamin A concentratio...

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Bibliographic Details
Published in:BMC research notes 2017-08, Vol.10 (1), p.421-421, Article 421
Main Authors: Qrafli, Mounia, El Kari, Khalid, Aguenaou, Hassan, Bourkadi, Jamal Eddine, Sadki, Khalid, El Mzibri, Mohammed
Format: Article
Language:English
Subjects:
Adaptive immunity
Adolescent
Adult
Case-Control Studies
Complications and side effects
Cytokines
Demographic aspects
Family medical history
Female
Geriatrics
Health care
High-performance liquid chromatography
Humans
Immune system
Male
Malnutrition
Micronutrients
Middle Aged
Morocco - ethnology
Plasma
Proteins
Risk factors
Supplements
Tuberculosis
Tuberculosis - blood
Tuberculosis - ethnology
Vitamin A
Vitamin A - blood
Vitamin A deficiency
Vitamin A Deficiency - blood
Vitamin A Deficiency - ethnology
Vitamin deficiency
Young Adult
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Summary:Vitamin A plays numerous roles in immune system. Its deficiency alters both the innate and adaptive immunity. Previous results reported that the micronutrients deficiency, particularly vitamin A, is observed in patients with tuberculosis. Thus, we aimed in this study to assess vitamin A concentrations in Moroccan patients with tuberculosis to set up a large efficacy study of vitamin A supplementation for TB infected patients. Plasma retinol concentration was measured by HPLC in 44 recently diagnosed TB patients and 40 healthy controls. We showed that plasma vitamin A is significantly lower in tuberculosis patients as compared to healthy controls (p 
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-017-2737-z