The chromosomal location of mouse interferon alpha genes

The chromosomal location of mouse leukocyte‐interferon (IFN‐alpha) genes was determined by Southern blot analysis of DNA from a panel of Chinese hamster x mouse somatic cell hybrids using a mouse IFN‐alpha cDNA as a hybridization probe. All resolvable mouse genes are located on mouse chromosome 4. I...

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Bibliographic Details
Published in:The EMBO journal 1984-07, Vol.3 (7), p.1643-1646
Main Authors: Lovett, M., Cox, D.R., Yee, D., Boll, W., Weissmann, C., Epstein, C.J., Epstein, L.B.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Chromosome Mapping
Classical genetics, quantitative genetics, hybrids
Fundamental and applied biological sciences. Psychology
Genes
Genetics of eukaryotes. Biological and molecular evolution
Interferon Type I - genetics
Mice - genetics
Polymorphism, Genetic
Vertebrata
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Summary:The chromosomal location of mouse leukocyte‐interferon (IFN‐alpha) genes was determined by Southern blot analysis of DNA from a panel of Chinese hamster x mouse somatic cell hybrids using a mouse IFN‐alpha cDNA as a hybridization probe. All resolvable mouse genes are located on mouse chromosome 4. In addition, two common restriction site polymorphisms within these genes were identified in several mouse strains.
ISSN:0261-4189
1460-2075
DOI:10.1002/j.1460-2075.1984.tb02023.x