Clinical Application of Fiber Visualization with LIC Maps Using Multidirectional Anisotropic Glyph Samples (A-Glyph LIC)

Recently, a fiber visualization method for high-angular resolution diffusion-weighted magnetic resonance imaging (MRI) data was proposed using a multiple-kernel line integral convolution (LIC) algorithm and an anisotropic spot pattern. This processing routine leads to high contrast color-coded LIC m...

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Bibliographic Details
Published in:Clinical neuroradiology (Munich) 2017-09, Vol.27 (3), p.263-273
Main Authors: Höller, M., Ehricke, H.-H., Synofzik, M., Klose, U., Groeschel, S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Algorithms
Anisotropy
Brain - diagnostic imaging
Child
Comparative analysis
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Humans
Image Processing, Computer-Assisted
Male
Medicine
Medicine & Public Health
Nerve Fibers, Myelinated
Neurology
Neuroradiology
Neurosurgery
NMR
Nuclear magnetic resonance
Original
Original Article
Visualization
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Summary:Recently, a fiber visualization method for high-angular resolution diffusion-weighted magnetic resonance imaging (MRI) data was proposed using a multiple-kernel line integral convolution (LIC) algorithm and an anisotropic spot pattern. This processing routine leads to high contrast color-coded LIC maps that are capable of visualizing local anisotropy information and regional fiber architecture. In this paper, we evaluate and validate this method by applying it to simulated datasets and to in vivo diffusion MRI data of children and adults with different disease conditions and healthy volunteers. Compared to routine clinical fiber visualization (color-coded fractional anisotropy, FA maps, and fiber tractography), it has the advantage of visualizing complex local fiber architecture in a fully automated way. The results indicate that this method is capable of reliably delineating normal fiber architecture and fibers infiltrated, displaced, or disrupted by lesions and is therefore a promising tool in the clinical context.
ISSN:1869-1439
1869-1447
DOI:10.1007/s00062-015-0486-8