Cost-effectiveness analysis of catch-up hepatitis A vaccination among unvaccinated/partially-vaccinated children

Highlights • Catch-up vaccination would reduce the number of infections by 741 and increase doses by 556,989. • Catch-up vaccination would increase net costs by $2.38 per person. • At 10 years old, the incremental cost of hepatitis A vaccine catch-up was $452,239 per QALY gained. • A catch-up vaccin...

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Bibliographic Details
Published in:Vaccine 2016-07, Vol.34 (35), p.4243-4249
Main Authors: Hankin-Wei, Abigail, Rein, David B, Hernandez-Romieu, Alfonso, Kennedy, Mallory J, Bulkow, Lisa, Rosenberg, Eli, Trigg, Monica, Nelson, Noele P
Format: Article
Language:English
Subjects:
Adolescent
Adults
Age
Allergy and Immunology
Child
Child, Preschool
Children & youth
Cost analysis
Cost-Benefit Analysis
Economic modeling
Economic models
Economics
Food contamination & poisoning
Hepatitis
Hepatitis A
Hepatitis A - prevention & control
Hepatitis A Vaccines - economics
Hepatitis A Vaccines - therapeutic use
Hepatitis A virus
Humans
Immunization, Secondary - economics
Infections
Liver diseases
Markov chains
Models, Economic
Population
Quality-Adjusted Life Years
Teenagers
Vaccination - economics
Vaccine recommendation
Vaccines
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Summary:Highlights • Catch-up vaccination would reduce the number of infections by 741 and increase doses by 556,989. • Catch-up vaccination would increase net costs by $2.38 per person. • At 10 years old, the incremental cost of hepatitis A vaccine catch-up was $452,239 per QALY gained. • A catch-up vaccination recommendation would be less cost effective than many other interventions.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2016.06.040