James Wenceslaus Papez, His Circuit, and Emotion

James Papez worked on the anatomical substrates of emotion and described a circuit, mainly composed of the hippocampus, thalamus and cingulum, and published his observations in 1937. However, such an idea existed before him, as evidenced by the rudimentary indications from Paul Broca, and Paul MacLe...

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Bibliographic Details
Published in:Annals of the Indian Academy of Neurology 2017-07, Vol.20 (3), p.207-210
Main Author: Bhattacharyya, Kalyan B
Format: Article
Language:English
Subjects:
Alzheimer's disease
Amnesia
Amygdala
Arousal
Behavior
Brain
Cerebellum
Cingulum
Cognitive ability
Dementia disorders
Emotions
History of Medicine
Hypothalamus
Limbic system
Memory
Movement disorders
Neural networks
Neuroanatomy
Neurodegenerative diseases
Neuroscientists
Nuclei
Papez,James
Parkinson's disease
Practice
Psychiatrists
Researchers
Semantic dementia
Septum
Temporal lobe
Thalamus
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Summary:James Papez worked on the anatomical substrates of emotion and described a circuit, mainly composed of the hippocampus, thalamus and cingulum, and published his observations in 1937. However, such an idea existed before him, as evidenced by the rudimentary indications from Paul Broca, and Paul MacLean added some other structures like, septum, amygdala, and hypothalamus in its ambit and called it the limbic system. Paul Ivan Yakovlev, proposed a circuit which also referred to orbitofrontal, insular, anterior temporal lobe, and other nuclei of thalamus. Further works hinted at cerebellar projections into this system and the clinical picture of aggression, arousal and positive feeding responses with stimulation of cerebellar nuclei, attests its possible role. Finally, the work of Heinrich Klüver and Paul Bucy of the United States of America on ablating the temporal lobes and amygdala and the resultant behaviour of the animals, almost incontrovertibly adduced evidence for the operation of a neural circuitry in the genesis of emotion. Additionally, Papez circuit may also be concerned with memory and damage to its various components in Parkinson's disease, Alzheimer's disease, Korsakoff's syndrome, semantic dementia, and global amnesia, where cognitive disturbance is almost universal, lends credence to its putative role.
ISSN:0972-2327
1998-3549
DOI:10.4103/aian.AIAN_487_16