The CHA2DS2-VASc Score as a Predictor of Left Atrial Thrombus in Patients with Non-Valvular Atrial Fibrillation

Objective: To investigate whether or not the CHA 2 DS 2 -VASc score predicts left atrial (LA) thrombus detected on pre-cardioversion transoesophageal echocardiography (TEE). Materials and Methods: The medical records of patients who had undergone TEE were reviewed to assess the presence of LA thromb...

Full description

Saved in:
Bibliographic Details
Published in:Medical principles and practice 2014, Vol.23 (3), p.234-238
Main Authors: Uz, Omer, Atalay, Murat, Doğan, Mehmet, Isilak, Zafer, Yalcin, Murat, Uzun, Mehmet, Kardesoglu, Ejder, Cebeci, Bekir Sitki
Format: Article
Language:English
Subjects:
Age Factors
Aged
Atrial Fibrillation - complications
Echocardiography, Transesophageal
Electric Countershock
Female
Health Status
Health Status Indicators
Humans
Incidence
Male
Middle Aged
Original Paper
Risk Assessment
Risk Factors
Sex Factors
Thrombosis - etiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: To investigate whether or not the CHA 2 DS 2 -VASc score predicts left atrial (LA) thrombus detected on pre-cardioversion transoesophageal echocardiography (TEE). Materials and Methods: The medical records of patients who had undergone TEE were reviewed to assess the presence of LA thrombus prior to direct-current cardioversion for atrial fibrillation (AF). The CHA 2 DS 2 -VASc score was calculated for each patient. Clinical TEE reports were reviewed for the presence of LA thrombus. Patients with a valve prosthesis or rheumatic mitral valve disease were excluded from this study. Results: A total of 309 patients were identified. The mean age was 70.1 ± 9.8 years and 151 (49%) patients were males and 158 (51%) were females. LA thrombus was seen in 32 (10.3%) of the 309 patients. Fifty (16.2%) patients had a low CHA 2 DS 2 -VASc score (0-1), 230 (74.4%) had an intermediate score (2-4) and 29 (9.4%) had a high score (5-9). The incidence of LA thrombus in the low, intermediate and high CHA 2 DS 2 -VASc score groups was 0, 4.4 and 68.7%, respectively. The LA thrombus risk increased with increasing CHA 2 DS 2 -VASc scores. On multivariate logistic analysis, the CHA 2 DS 2 -VASc score (OR 3.26, 95% CI 2.3-4.65; p = 0.001) and age (OR 0.93, 95% CI 0.88-0.98; p = 0.004) were independent risk factors for LA thrombus in patients with non-valvular AF. Conclusion: A high CHA 2 DS 2 -VASc score was independently associated with the presence of LA thrombus in patients with non-valvular AF.
ISSN:1011-7571
1423-0151
DOI:10.1159/000361028