Performance of the Pooled Cohort atherosclerotic cardiovascular disease risk score in hepatitis C virus‐infected persons

Summary Chronic hepatitis C virus (HCV) infection has been associated with an increased risk for cardiovascular disease (CVD). The recommended Pooled Cohort atherosclerotic cardiovascular disease (ASCVD) risk equation for estimation of 10‐year CVD risk has not been validated in HCV‐infected populati...

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Bibliographic Details
Published in:Journal of viral hepatitis 2017-10, Vol.24 (10), p.814-822
Main Authors: Chew, K. W., Bhattacharya, D., Horwich, T. B., Yan, P., McGinnis, K. A., Tseng, C., Freiberg, M. S., Currier, J. S., Butt, A. A.
Format: Article
Language:English
Subjects:
Aged
Arteriosclerosis
Atherosclerosis
Atherosclerosis - epidemiology
Atherosclerosis - etiology
atherosclerotic cardiovascular disease score
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
cardiovascular risk assessment
Cholesterol
Chronic infection
Comorbidity
Coronary artery disease
Female
Health risk assessment
Heart diseases
Hepacivirus
Hepatitis
Hepatitis B
Hepatitis C
Hepatitis C - complications
Hepatitis C - virology
hepatitis C virus
Humans
Incidence
Infections
Low density lipoprotein
Male
Middle Aged
Population Surveillance
Proportional Hazards Models
Reproducibility of Results
Retrospective Studies
Risk Assessment
Risk Factors
Statistics
Stroke
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Summary:Summary Chronic hepatitis C virus (HCV) infection has been associated with an increased risk for cardiovascular disease (CVD). The recommended Pooled Cohort atherosclerotic cardiovascular disease (ASCVD) risk equation for estimation of 10‐year CVD risk has not been validated in HCV‐infected populations. We examined the performance of the ASCVD risk score in HCV‐infected persons, using the national Electronically Retrieved Cohort of HCV Infected Veterans to derive a cohort of HCV‐infected and uninfected subjects without baseline ASCVD, hepatitis B, or HIV infection, and with low‐density lipoprotein cholesterol level
ISSN:1352-0504
1365-2893
DOI:10.1111/jvh.12705