Comparison of PASL, PCASL, and background‐suppressed 3D PCASL in mild cognitive impairment

We compared three implementations of single‐shot arterial spin labeled (ASL) perfusion magnetic resonance imaging: two‐dimensional (2D) pulsed ASL (PASL), 2D pseudocontinuous ASL (PCASL), and background‐suppressed (BS) 3D PCASL obtained in a cohort of patients with mild cognitive impairment (MCI) an...

Full description

Saved in:
Bibliographic Details
Published in:Human brain mapping 2017-10, Vol.38 (10), p.5260-5273
Main Authors: Dolui, Sudipto, Vidorreta, Marta, Wang, Ze, Nasrallah, Ilya M., Alavi, Abass, Wolk, David A., Detre, John A.
Format: Article
Language:English
Subjects:
3D spiral acquisition
Aged
background suppression
Biomarkers
Blood flow
Brain
Brain - diagnostic imaging
Brain - metabolism
Brain Mapping
Cerebral blood flow
Cognitive ability
Cognitive Dysfunction - diagnostic imaging
Cognitive Dysfunction - metabolism
Cohort Studies
Cortex (cingulate)
Cortex (parietal)
Cortex (temporal)
Differentiation
Educational Status
Emission analysis
Emissions control
Female
Fluorodeoxyglucose F18
Geriatrics
Hippocampus
Humans
Hypometabolism
Imaging, Three-Dimensional
Impairment
Labelling
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Marking
Mental Status Schedule
mild cognitive impairment
Neuroimaging
Older people
Patients
Perfusion
Positron emission
Positron emission tomography
pseudocontinuous ASL
pulsed ASL
Radiopharmaceuticals
Substantia alba
Substantia grisea
Tomography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We compared three implementations of single‐shot arterial spin labeled (ASL) perfusion magnetic resonance imaging: two‐dimensional (2D) pulsed ASL (PASL), 2D pseudocontinuous ASL (PCASL), and background‐suppressed (BS) 3D PCASL obtained in a cohort of patients with mild cognitive impairment (MCI) and elderly controls. Study subjects also underwent 18F‐fluorodeoxyglucose positron emission tomography (18F‐FDG PET). While BS 3D PCASL showed the lowest (P 
ISSN:1065-9471
1097-0193
DOI:10.1002/hbm.23732