Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group

• Published in: Blood cancer journal (New York) 2017-08, Vol.7 (8), p.e599-e599
• Main Authors: Hillengass, J, Moulopoulos, L A, Delorme, S, Koutoulidis, V, Mosebach, J, Hielscher, T, Drake, M, Rajkumar, S V, Oestergaard, B, Abildgaard, N, Hinge, M, Plesner, T, Suehara, Y, Matsue, K, Withofs, N, Caers, J, Waage, A, Goldschmidt, H, Dimopoulos, M A, Lentzsch, S, Durie, B, Terpos, E
• Format: Article
• Language: English
• Subjects: 631/67/2321; 692/699/1541/1990/804; Adult; Aged; Aged, 80 and over; Biomedical and Life Sciences; Biomedicine; Cancer Research; Disease-Free Survival; Female; Hematology; Human health sciences; Humans; Hématologie; Male; Middle Aged; Multiple myeloma; Multiple Myeloma - diagnostic imaging; Multiple Myeloma - mortality; Oncology; Original; original-article; Osteolysis - diagnostic imaging; Osteolysis - mortality; Plasma; Positron-Emission Tomography; Retrospective Studies; Sciences de la santé humaine; Survival Rate; Tomography; Tomography, X-Ray Computed
• ISSN: 2044-5385; 2044-5385
• DOI: 10.1038/bcj.2017.78

For decades, conventional skeletal survey (CSS) has been the standard imaging technique for multiple myeloma (MM). However, recently whole-body computed tomography (WBCT) has been implemented into the diagnostic criteria of MM. This analysis compares sensitivity and prognostic significance of WBCT and CSS in patients with smoldering MM (SMM) and MM. Fifty-four of 212 patients (25.5%) had a negative CSS and a positive WBCT for osteolytic lesions ( P