Digging into the low molecular weight peptidome with the OligoNet web server

Bioactive peptides play critical roles in regulating many biological processes. Recently, natural short peptides biomarkers are drawing significant attention and are considered as “hidden treasure” of drug candidates. High resolution and high mass accuracy provided by mass spectrometry (MS)-based un...

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Bibliographic Details
Published in:Scientific reports 2017-09, Vol.7 (1), p.11692-9, Article 11692
Main Authors: Liu, Youzhong, Forcisi, Sara, Lucio, Marianna, Harir, Mourad, Bahut, Florian, Deleris-Bou, Magali, Krieger-Weber, Sibylle, Gougeon, Régis D., Alexandre, Hervé, Schmitt-Kopplin, Philippe
Format: Article
Language:English
Subjects:
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631/114/2408
631/45/611
631/92/320
82/81
Amino acids
Biodegradation
Biological Factors - analysis
Biological Factors - genetics
Computational Biology - methods
Data interpretation
Data processing
Drug development
Humanities and Social Sciences
Internet
Life Sciences
Mass spectrometry
Mass spectroscopy
Metabolic networks
Metabolism
Metabolomics
Metabolomics - methods
Molecular weight
multidisciplinary
Peptides
Peptides - analysis
Peptides - genetics
Science
Science (multidisciplinary)
Yeasts
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Description
Summary:Bioactive peptides play critical roles in regulating many biological processes. Recently, natural short peptides biomarkers are drawing significant attention and are considered as “hidden treasure” of drug candidates. High resolution and high mass accuracy provided by mass spectrometry (MS)-based untargeted metabolomics would enable the rapid detection and wide coverage of the low-molecular-weight peptidome. However, translating unknown masses (
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-017-11786-w