Association among obesity, overweight and autism spectrum disorder: a systematic review and meta-analysis

Obesity, overweight and autism spectrum disorder (ASD) remain serious public health problems. Although lots of studies have recently explored the association among obesity, overweight and ASD, the findings are inconsistent. Thus, we conducted a meta-analysis of epidemiological studies to examine the...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2017-09, Vol.7 (1), p.11697-9, Article 11697
Main Authors: Zheng, Zhen, Zhang, Li, Li, Shiping, Zhao, Fengyan, Wang, Yan, Huang, Lan, Huang, Jinglan, Zou, Rong, Qu, Yi, Mu, Dezhi
Format: Article
Language:English
Subjects:
692/699/476/1373
692/700/2817
Autism
Body weight
Health problems
Humanities and Social Sciences
Meta-analysis
multidisciplinary
Obesity
Overweight
Public health
Science
Science (multidisciplinary)
Sensitivity analysis
Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Obesity, overweight and autism spectrum disorder (ASD) remain serious public health problems. Although lots of studies have recently explored the association among obesity, overweight and ASD, the findings are inconsistent. Thus, we conducted a meta-analysis of epidemiological studies to examine the association among obesity, overweight and ASD. PubMed, Embase, and the Cochrane Library were used for literature searches to identify eligible studies published in English before November 15, 2016. Relevant studies estimating the association among obesity, overweight and ASD were included. Fifteen studies encompassing 49,937,078 participants and 1,045,538 individuals with ASD were included in this study. A random effects model was chosen to synthesize the effect sizes of individual studies. The prevalence of obesity was significantly higher in individuals with ASD than in controls (OR = 1.84, 95% confidence interval [CI]: 1.37–2.48, P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-017-12003-4