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Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study
Objectives To investigate whether subchondral bone structure from plain radiographs is different between subjects with and without articular cartilage damage or bone marrow lesions (BMLs). Methods Radiography-based bone structure was assessed from 80 subjects with different stages of knee osteoarthr...
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| Published in: | European radiology 2017-11, Vol.27 (11), p.4874-4882 |
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| container_title | European radiology |
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| creator | Hirvasniemi, Jukka Thevenot, Jérôme Guermazi, Ali Podlipská, Jana Roemer, Frank W. Nieminen, Miika T. Saarakkala, Simo |
| description | Objectives
To investigate whether subchondral bone structure from plain radiographs is different between subjects with and without articular cartilage damage or bone marrow lesions (BMLs).
Methods
Radiography-based bone structure was assessed from 80 subjects with different stages of knee osteoarthritis using entropy of Laplacian-based image (E
Lap
) and local binary patterns (E
LBP
), homogeneity index of local angles (HI
Angles,mean
), and horizontal (FD
Hor
) and vertical fractal dimensions (FD
Ver
). Medial tibial articular cartilage damage and BMLs were scored using the magnetic resonance imaging osteoarthritis knee score. Level of statistical significance was set to
p
|
| doi_str_mv | 10.1007/s00330-017-4826-8 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5635082</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1949490959</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-bc9032943ea36f2df2f4d0f5d3167aedfe37d63fde9bc21eaa99aac4d7bf97a83</originalsourceid><addsrcrecordid>eNp1Uk2LFDEQbURx19Uf4EUCXry0Jp1Md-ciyK5fuDAXPYfqpDKdtScZ87HD_jl_mxlnXVZBUlAF9epVvfCa5jmjrxmlw5tEKee0pWxoxdj17figOWWCdy2jo3jYnFLJx3aQUpw0T1K6opRKJobHzUk3Ci57IU-bnxfOWozoNSbiPMlucrCQVCY9B29irafgkaQci84lIsFrWApkNKQk5zdkt0Cdi2Bc2ETYzYlMmPeInnz3WEn3Ls8EvPldhJKJhpjdAhskBraHFOJxxxZiDHuyYHLBJ9KSPCNZl6WQL5WJrFPGUGfn6LJL9aJibp42jywsCZ_d5rPm24f3X88_tZfrj5_P3122Wgw0t5OWlHdScATe287YzgpD7cpw1g-AxiIfTM-tQTnpjiGAlABamGGycoCRnzVvj7y7Mm3RaPS5fo3aRVePvlEBnPq7492sNuFarXq-omNXCV7dEsTwo2DKauuSxmUBj6EkxUZZo19JVqEv_4FehRJ9laeYFPVRuZIVxY4oHUNKEe3dMYyqgzvU0R2qukMd3KEOKl7cV3E38ccOFdAdAam2_AbjvdX_Zf0FjqPMkA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1949490959</pqid></control><display><type>article</type><title>Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study</title><source>Springer Nature</source><creator>Hirvasniemi, Jukka ; Thevenot, Jérôme ; Guermazi, Ali ; Podlipská, Jana ; Roemer, Frank W. ; Nieminen, Miika T. ; Saarakkala, Simo</creator><creatorcontrib>Hirvasniemi, Jukka ; Thevenot, Jérôme ; Guermazi, Ali ; Podlipská, Jana ; Roemer, Frank W. ; Nieminen, Miika T. ; Saarakkala, Simo</creatorcontrib><description>Objectives
To investigate whether subchondral bone structure from plain radiographs is different between subjects with and without articular cartilage damage or bone marrow lesions (BMLs).
Methods
Radiography-based bone structure was assessed from 80 subjects with different stages of knee osteoarthritis using entropy of Laplacian-based image (E
Lap
) and local binary patterns (E
LBP
), homogeneity index of local angles (HI
Angles,mean
), and horizontal (FD
Hor
) and vertical fractal dimensions (FD
Ver
). Medial tibial articular cartilage damage and BMLs were scored using the magnetic resonance imaging osteoarthritis knee score. Level of statistical significance was set to
p
< 0.05.
Results
Subjects with medial tibial cartilage damage had significantly higher FD
Ver
and E
LBP
as well as lower E
Lap
and HI
Angles,mean
in the medial tibial subchondral bone region than subjects without damage. FD
Hor
, FD
Ver
, and E
LBP
were significantly higher, whereas E
Lap
and HI
Angles,mean
were lower in the medial trabecular bone region. Subjects with medial tibial BMLs had significantly higher FD
Ver
and E
LBP
as well as lower E
Lap
and HI
Angles,mean
in medial tibial subchondral bone. FD
Hor
, FD
Ver
, and E
LBP
were higher, whereas E
Lap
and HI
Angles,mean
were lower in medial trabecular bone.
Conclusions
Our results support the use of bone structural analysis from radiographs when examining subjects with osteoarthritis or at risk of having it.
Key points
•
Knee osteoarthritis causes changes in articular cartilage and subchondral bone
•
Magnetic resonance imaging is a comprehensive imaging modality for knee osteoarthritis
•
Radiography
-
based bone structure analysis can provide additional information of osteoarthritic subjects</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-017-4826-8</identifier><identifier>PMID: 28439649</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Arthritis ; Biocompatibility ; Bone imaging ; Bone marrow ; Bone Marrow - diagnostic imaging ; Bone Marrow - pathology ; Cancellous bone ; Cancellous Bone - diagnostic imaging ; Cancellous Bone - pathology ; Cartilage ; Cartilage (articular) ; Cartilage diseases ; Cartilage, Articular - diagnostic imaging ; Cartilage, Articular - pathology ; Cross-Sectional Studies ; Damage assessment ; Diagnostic Radiology ; Entropy ; Female ; Fractals ; Homogeneity ; Humans ; Imaging ; Internal Medicine ; Interventional Radiology ; Knee ; Knee Joint - diagnostic imaging ; Knee Joint - pathology ; Lesions ; Magnetic Resonance Imaging ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Musculoskeletal ; Neuroradiology ; NMR ; Nuclear magnetic resonance ; Osteoarthritis ; Osteoarthritis, Knee - diagnostic imaging ; Osteoarthritis, Knee - pathology ; Radiographs ; Radiography ; Radiology ; Resonance ; Structural analysis ; Subchondral bone ; Tibia - diagnostic imaging ; Tibia - pathology ; Ultrasound</subject><ispartof>European radiology, 2017-11, Vol.27 (11), p.4874-4882</ispartof><rights>The Author(s) 2017</rights><rights>European Radiology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-bc9032943ea36f2df2f4d0f5d3167aedfe37d63fde9bc21eaa99aac4d7bf97a83</citedby><cites>FETCH-LOGICAL-c470t-bc9032943ea36f2df2f4d0f5d3167aedfe37d63fde9bc21eaa99aac4d7bf97a83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28439649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirvasniemi, Jukka</creatorcontrib><creatorcontrib>Thevenot, Jérôme</creatorcontrib><creatorcontrib>Guermazi, Ali</creatorcontrib><creatorcontrib>Podlipská, Jana</creatorcontrib><creatorcontrib>Roemer, Frank W.</creatorcontrib><creatorcontrib>Nieminen, Miika T.</creatorcontrib><creatorcontrib>Saarakkala, Simo</creatorcontrib><title>Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
To investigate whether subchondral bone structure from plain radiographs is different between subjects with and without articular cartilage damage or bone marrow lesions (BMLs).
Methods
Radiography-based bone structure was assessed from 80 subjects with different stages of knee osteoarthritis using entropy of Laplacian-based image (E
Lap
) and local binary patterns (E
LBP
), homogeneity index of local angles (HI
Angles,mean
), and horizontal (FD
Hor
) and vertical fractal dimensions (FD
Ver
). Medial tibial articular cartilage damage and BMLs were scored using the magnetic resonance imaging osteoarthritis knee score. Level of statistical significance was set to
p
< 0.05.
Results
Subjects with medial tibial cartilage damage had significantly higher FD
Ver
and E
LBP
as well as lower E
Lap
and HI
Angles,mean
in the medial tibial subchondral bone region than subjects without damage. FD
Hor
, FD
Ver
, and E
LBP
were significantly higher, whereas E
Lap
and HI
Angles,mean
were lower in the medial trabecular bone region. Subjects with medial tibial BMLs had significantly higher FD
Ver
and E
LBP
as well as lower E
Lap
and HI
Angles,mean
in medial tibial subchondral bone. FD
Hor
, FD
Ver
, and E
LBP
were higher, whereas E
Lap
and HI
Angles,mean
were lower in medial trabecular bone.
Conclusions
Our results support the use of bone structural analysis from radiographs when examining subjects with osteoarthritis or at risk of having it.
Key points
•
Knee osteoarthritis causes changes in articular cartilage and subchondral bone
•
Magnetic resonance imaging is a comprehensive imaging modality for knee osteoarthritis
•
Radiography
-
based bone structure analysis can provide additional information of osteoarthritic subjects</description><subject>Adult</subject><subject>Aged</subject><subject>Arthritis</subject><subject>Biocompatibility</subject><subject>Bone imaging</subject><subject>Bone marrow</subject><subject>Bone Marrow - diagnostic imaging</subject><subject>Bone Marrow - pathology</subject><subject>Cancellous bone</subject><subject>Cancellous Bone - diagnostic imaging</subject><subject>Cancellous Bone - pathology</subject><subject>Cartilage</subject><subject>Cartilage (articular)</subject><subject>Cartilage diseases</subject><subject>Cartilage, Articular - diagnostic imaging</subject><subject>Cartilage, Articular - pathology</subject><subject>Cross-Sectional Studies</subject><subject>Damage assessment</subject><subject>Diagnostic Radiology</subject><subject>Entropy</subject><subject>Female</subject><subject>Fractals</subject><subject>Homogeneity</subject><subject>Humans</subject><subject>Imaging</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Knee</subject><subject>Knee Joint - diagnostic imaging</subject><subject>Knee Joint - pathology</subject><subject>Lesions</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Musculoskeletal</subject><subject>Neuroradiology</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Osteoarthritis</subject><subject>Osteoarthritis, Knee - diagnostic imaging</subject><subject>Osteoarthritis, Knee - pathology</subject><subject>Radiographs</subject><subject>Radiography</subject><subject>Radiology</subject><subject>Resonance</subject><subject>Structural analysis</subject><subject>Subchondral bone</subject><subject>Tibia - diagnostic imaging</subject><subject>Tibia - pathology</subject><subject>Ultrasound</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp1Uk2LFDEQbURx19Uf4EUCXry0Jp1Md-ciyK5fuDAXPYfqpDKdtScZ87HD_jl_mxlnXVZBUlAF9epVvfCa5jmjrxmlw5tEKee0pWxoxdj17figOWWCdy2jo3jYnFLJx3aQUpw0T1K6opRKJobHzUk3Ci57IU-bnxfOWozoNSbiPMlucrCQVCY9B29irafgkaQci84lIsFrWApkNKQk5zdkt0Cdi2Bc2ETYzYlMmPeInnz3WEn3Ls8EvPldhJKJhpjdAhskBraHFOJxxxZiDHuyYHLBJ9KSPCNZl6WQL5WJrFPGUGfn6LJL9aJibp42jywsCZ_d5rPm24f3X88_tZfrj5_P3122Wgw0t5OWlHdScATe287YzgpD7cpw1g-AxiIfTM-tQTnpjiGAlABamGGycoCRnzVvj7y7Mm3RaPS5fo3aRVePvlEBnPq7492sNuFarXq-omNXCV7dEsTwo2DKauuSxmUBj6EkxUZZo19JVqEv_4FehRJ9laeYFPVRuZIVxY4oHUNKEe3dMYyqgzvU0R2qukMd3KEOKl7cV3E38ccOFdAdAam2_AbjvdX_Zf0FjqPMkA</recordid><startdate>20171101</startdate><enddate>20171101</enddate><creator>Hirvasniemi, Jukka</creator><creator>Thevenot, Jérôme</creator><creator>Guermazi, Ali</creator><creator>Podlipská, Jana</creator><creator>Roemer, Frank W.</creator><creator>Nieminen, Miika T.</creator><creator>Saarakkala, Simo</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20171101</creationdate><title>Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study</title><author>Hirvasniemi, Jukka ; Thevenot, Jérôme ; Guermazi, Ali ; Podlipská, Jana ; Roemer, Frank W. ; Nieminen, Miika T. ; Saarakkala, Simo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-bc9032943ea36f2df2f4d0f5d3167aedfe37d63fde9bc21eaa99aac4d7bf97a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Arthritis</topic><topic>Biocompatibility</topic><topic>Bone imaging</topic><topic>Bone marrow</topic><topic>Bone Marrow - diagnostic imaging</topic><topic>Bone Marrow - pathology</topic><topic>Cancellous bone</topic><topic>Cancellous Bone - diagnostic imaging</topic><topic>Cancellous Bone - pathology</topic><topic>Cartilage</topic><topic>Cartilage (articular)</topic><topic>Cartilage diseases</topic><topic>Cartilage, Articular - diagnostic imaging</topic><topic>Cartilage, Articular - pathology</topic><topic>Cross-Sectional Studies</topic><topic>Damage assessment</topic><topic>Diagnostic Radiology</topic><topic>Entropy</topic><topic>Female</topic><topic>Fractals</topic><topic>Homogeneity</topic><topic>Humans</topic><topic>Imaging</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Knee</topic><topic>Knee Joint - diagnostic imaging</topic><topic>Knee Joint - pathology</topic><topic>Lesions</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Musculoskeletal</topic><topic>Neuroradiology</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Osteoarthritis</topic><topic>Osteoarthritis, Knee - diagnostic imaging</topic><topic>Osteoarthritis, Knee - pathology</topic><topic>Radiographs</topic><topic>Radiography</topic><topic>Radiology</topic><topic>Resonance</topic><topic>Structural analysis</topic><topic>Subchondral bone</topic><topic>Tibia - diagnostic imaging</topic><topic>Tibia - pathology</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hirvasniemi, Jukka</creatorcontrib><creatorcontrib>Thevenot, Jérôme</creatorcontrib><creatorcontrib>Guermazi, Ali</creatorcontrib><creatorcontrib>Podlipská, Jana</creatorcontrib><creatorcontrib>Roemer, Frank W.</creatorcontrib><creatorcontrib>Nieminen, Miika T.</creatorcontrib><creatorcontrib>Saarakkala, Simo</creatorcontrib><collection>SpringerOpen</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies & Aerospace Database (1962 - current)</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirvasniemi, Jukka</au><au>Thevenot, Jérôme</au><au>Guermazi, Ali</au><au>Podlipská, Jana</au><au>Roemer, Frank W.</au><au>Nieminen, Miika T.</au><au>Saarakkala, Simo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2017-11-01</date><risdate>2017</risdate><volume>27</volume><issue>11</issue><spage>4874</spage><epage>4882</epage><pages>4874-4882</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
To investigate whether subchondral bone structure from plain radiographs is different between subjects with and without articular cartilage damage or bone marrow lesions (BMLs).
Methods
Radiography-based bone structure was assessed from 80 subjects with different stages of knee osteoarthritis using entropy of Laplacian-based image (E
Lap
) and local binary patterns (E
LBP
), homogeneity index of local angles (HI
Angles,mean
), and horizontal (FD
Hor
) and vertical fractal dimensions (FD
Ver
). Medial tibial articular cartilage damage and BMLs were scored using the magnetic resonance imaging osteoarthritis knee score. Level of statistical significance was set to
p
< 0.05.
Results
Subjects with medial tibial cartilage damage had significantly higher FD
Ver
and E
LBP
as well as lower E
Lap
and HI
Angles,mean
in the medial tibial subchondral bone region than subjects without damage. FD
Hor
, FD
Ver
, and E
LBP
were significantly higher, whereas E
Lap
and HI
Angles,mean
were lower in the medial trabecular bone region. Subjects with medial tibial BMLs had significantly higher FD
Ver
and E
LBP
as well as lower E
Lap
and HI
Angles,mean
in medial tibial subchondral bone. FD
Hor
, FD
Ver
, and E
LBP
were higher, whereas E
Lap
and HI
Angles,mean
were lower in medial trabecular bone.
Conclusions
Our results support the use of bone structural analysis from radiographs when examining subjects with osteoarthritis or at risk of having it.
Key points
•
Knee osteoarthritis causes changes in articular cartilage and subchondral bone
•
Magnetic resonance imaging is a comprehensive imaging modality for knee osteoarthritis
•
Radiography
-
based bone structure analysis can provide additional information of osteoarthritic subjects</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28439649</pmid><doi>10.1007/s00330-017-4826-8</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0938-7994 |
| ispartof | European radiology, 2017-11, Vol.27 (11), p.4874-4882 |
| issn | 0938-7994 1432-1084 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5635082 |
| source | Springer Nature |
| subjects | Adult Aged Arthritis Biocompatibility Bone imaging Bone marrow Bone Marrow - diagnostic imaging Bone Marrow - pathology Cancellous bone Cancellous Bone - diagnostic imaging Cancellous Bone - pathology Cartilage Cartilage (articular) Cartilage diseases Cartilage, Articular - diagnostic imaging Cartilage, Articular - pathology Cross-Sectional Studies Damage assessment Diagnostic Radiology Entropy Female Fractals Homogeneity Humans Imaging Internal Medicine Interventional Radiology Knee Knee Joint - diagnostic imaging Knee Joint - pathology Lesions Magnetic Resonance Imaging Male Medicine Medicine & Public Health Middle Aged Musculoskeletal Neuroradiology NMR Nuclear magnetic resonance Osteoarthritis Osteoarthritis, Knee - diagnostic imaging Osteoarthritis, Knee - pathology Radiographs Radiography Radiology Resonance Structural analysis Subchondral bone Tibia - diagnostic imaging Tibia - pathology Ultrasound |
| title | Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study |
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