Risk factors for metachronous adenoma in the residual colon of patients undergoing curative surgery for colorectal cancer

Purpose Adenoma detection in colorectal cancer survivors is poorly characterised with insufficient evidence to inform frequency of surveillance schedule. The aim of this study was to examine adenoma incidence and recurrence in patients who have undergone colorectal cancer resection with curative int...

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Bibliographic Details
Published in:International journal of colorectal disease 2017-11, Vol.32 (11), p.1609-1616
Main Authors: Patel, Abhilasha, Williams, Nigel, Parsons, Nicholas, Ali, Omar, Peters, Francesca, Ranat, Reesha, Shah, Jasmine, Spector, Emma, Arasaradnam, Ramesh P.
Format: Article
Language:English
Subjects:
Adenoma
Adenoma - epidemiology
Adenoma - pathology
Cancer
Cancer patients
Colectomy - adverse effects
Colectomy - methods
Colonoscopy
Colonoscopy - methods
Colonoscopy - statistics & numerical data
Colorectal cancer
Colorectal carcinoma
Colorectal Neoplasms - mortality
Colorectal Neoplasms - pathology
Colorectal Neoplasms - surgery
Diagnosis
Disease-Free Survival
Diseases
Endoscopy
Female
Gastroenterology
Hepatology
Humans
Incidence
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Recurrence, Local - epidemiology
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Neoplasms, Multiple Primary - epidemiology
Neoplasms, Multiple Primary - pathology
Neoplasms, Second Primary - epidemiology
Neoplasms, Second Primary - pathology
Oncology, Experimental
Original
Original Article
Patient Care Planning
Proctology
Relapse
Risk Assessment - methods
Risk Factors
Sex Factors
Surgery
Surveillance
Survival
Tumors
United Kingdom - epidemiology
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Summary:Purpose Adenoma detection in colorectal cancer survivors is poorly characterised with insufficient evidence to inform frequency of surveillance schedule. The aim of this study was to examine adenoma incidence and recurrence in patients who have undergone colorectal cancer resection with curative intent. Survival outcomes were compared to determine if the presence of adenomas could be used to identify patients at higher risk of local recurrence. Methods This is a retrospective observational cohort study at a single tertiary institution between 2006 and 2012. Five hundred fifteen consecutive patients with stage I–III colorectal cancer who had preoperative colonoscopy and curative surgery were included (median follow-up 56 months (36–75 months). Results In total, 352/515 (68%) patients underwent postoperative surveillance colonoscopy in the first 5 years after resection. Male gender was associated with greater risk of detecting synchronous adenoma at index colonoscopy or in the resection specimen (OR 2.35, p  
ISSN:0179-1958
1432-1262
DOI:10.1007/s00384-017-2881-x