Expression of CeHSP17 Protein in Response to Heat Shock and Heavy Metal Ions

Small heat shock proteins (sHSP) are ubiquitously found in all organisms, and with other heat shock proteins (HSP) such as HSP60, HSP70, HSP90, HSP100 made up the molecular chaperone family. They are involved in a wide range of biological processes which include among others cell resistance to biolo...

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Bibliographic Details
Published in:Journal of nematology 2017-09, Vol.49 (3), p.168-176
Main Authors: Ezemaduka, Anastasia N., Wang, Yunbiao, Li, Xiujun
Format: Article
Language:English
Subjects:
biomarker
cadmium
CeHSP17
Free-living Nematodes
small heat shock proteins
zinc
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Summary:Small heat shock proteins (sHSP) are ubiquitously found in all organisms, and with other heat shock proteins (HSP) such as HSP60, HSP70, HSP90, HSP100 made up the molecular chaperone family. They are involved in a wide range of biological processes which include among others cell resistance to biological and environmental stress conditions. In this study, we show by western blotting that CeHSP17, an sHSP of , is significantly induced by high temperatures. Furthermore, in response to metal stress, the CeHSP17 protein expression was significantly induced by cadmium and zinc at high concentration of clearly cytotoxic range in wild-type . Altogether, our results show the involvement of CeHSP17 protein in both environmental and biological stresses in and establish for the first time the expression pattern of the CeHSP17 protein in response to thermal and metal stress conditions in . The responses of CeHSP17 protein expression may serve as potential sensitive biomarker for metal-induced toxicity monitoring and environmental risk assessment.
ISSN:0022-300X
2640-396X
DOI:10.21307/jofnem-2017-081