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Expression of CeHSP17 Protein in Response to Heat Shock and Heavy Metal Ions
Small heat shock proteins (sHSP) are ubiquitously found in all organisms, and with other heat shock proteins (HSP) such as HSP60, HSP70, HSP90, HSP100 made up the molecular chaperone family. They are involved in a wide range of biological processes which include among others cell resistance to biolo...
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| Published in: | Journal of nematology 2017-09, Vol.49 (3), p.168-176 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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| container_end_page | 176 |
| container_issue | 3 |
| container_start_page | 168 |
| container_title | Journal of nematology |
| container_volume | 49 |
| creator | Ezemaduka, Anastasia N. Wang, Yunbiao Li, Xiujun |
| description | Small heat shock proteins (sHSP) are ubiquitously found in all organisms, and with other heat shock proteins (HSP) such as HSP60, HSP70, HSP90, HSP100 made up the molecular chaperone family. They are involved in a wide range of biological processes which include among others cell resistance to biological and environmental stress conditions. In this study, we show by western blotting that CeHSP17, an sHSP of
, is significantly induced by high temperatures. Furthermore, in response to metal stress, the CeHSP17 protein expression was significantly induced by cadmium and zinc at high concentration of clearly cytotoxic range in wild-type
. Altogether, our results show the involvement of CeHSP17 protein in both environmental and biological stresses in
and establish for the first time the expression pattern of the CeHSP17 protein in response to thermal and metal stress conditions in
. The responses of CeHSP17 protein expression may serve as potential sensitive biomarker for metal-induced toxicity monitoring and environmental risk assessment. |
| doi_str_mv | 10.21307/jofnem-2017-081 |
| format | article |
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, is significantly induced by high temperatures. Furthermore, in response to metal stress, the CeHSP17 protein expression was significantly induced by cadmium and zinc at high concentration of clearly cytotoxic range in wild-type
. Altogether, our results show the involvement of CeHSP17 protein in both environmental and biological stresses in
and establish for the first time the expression pattern of the CeHSP17 protein in response to thermal and metal stress conditions in
. The responses of CeHSP17 protein expression may serve as potential sensitive biomarker for metal-induced toxicity monitoring and environmental risk assessment.</description><identifier>ISSN: 0022-300X</identifier><identifier>EISSN: 2640-396X</identifier><identifier>DOI: 10.21307/jofnem-2017-081</identifier><identifier>PMID: 29062158</identifier><language>eng</language><publisher>United States: Sciendo</publisher><subject>biomarker ; cadmium ; CeHSP17 ; Free-living Nematodes ; small heat shock proteins ; zinc</subject><ispartof>Journal of nematology, 2017-09, Vol.49 (3), p.168-176</ispartof><rights>The Society of Nematologists 2017 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644928/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644928/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29062158$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ezemaduka, Anastasia N.</creatorcontrib><creatorcontrib>Wang, Yunbiao</creatorcontrib><creatorcontrib>Li, Xiujun</creatorcontrib><title>Expression of CeHSP17 Protein in Response to Heat Shock and Heavy Metal Ions</title><title>Journal of nematology</title><addtitle>J Nematol</addtitle><description>Small heat shock proteins (sHSP) are ubiquitously found in all organisms, and with other heat shock proteins (HSP) such as HSP60, HSP70, HSP90, HSP100 made up the molecular chaperone family. They are involved in a wide range of biological processes which include among others cell resistance to biological and environmental stress conditions. In this study, we show by western blotting that CeHSP17, an sHSP of
, is significantly induced by high temperatures. Furthermore, in response to metal stress, the CeHSP17 protein expression was significantly induced by cadmium and zinc at high concentration of clearly cytotoxic range in wild-type
. Altogether, our results show the involvement of CeHSP17 protein in both environmental and biological stresses in
and establish for the first time the expression pattern of the CeHSP17 protein in response to thermal and metal stress conditions in
. The responses of CeHSP17 protein expression may serve as potential sensitive biomarker for metal-induced toxicity monitoring and environmental risk assessment.</description><subject>biomarker</subject><subject>cadmium</subject><subject>CeHSP17</subject><subject>Free-living Nematodes</subject><subject>small heat shock proteins</subject><subject>zinc</subject><issn>0022-300X</issn><issn>2640-396X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpVUU1P3DAQtVBRWWjvnCofewn1OLYTX5CqFXSRtgIBlbhZ3ngC2Wbt1E6g--9rylcrjTSfem_0HiGHwI44lKz6sg6tx03BGVQFq2GHzLgSrCi1unlHZoxxXpSM3eyR_ZTWjOU5qPdkj2umOMh6RpYnv4eIKXXB09DSOS6uLqCiFzGM2Hma4xLTEHxCOga6QDvSq7vQ_KTWu8f2fku_42h7epZvPpDd1vYJPz7nA_Lj9OR6viiW59_O5l-XxVByGAtrQVstEORKgHONlLK2JRMoatDQOt4qVzZ5X1kpWqtXTlayAaeVaGoFWB6Q4yfcYVpt0DXox2h7M8RuY-PWBNuZ_ze-uzO34d5IJYTmdQb4_AwQw68J02g2XWqw763HMCUDWsqsEBc6n376l-uV5EXCt2cebD9idHgbp20uzDpM0WcZDDDz1y3z5JZ5dMtktzI6qLr8Azy-iNw</recordid><startdate>20170901</startdate><enddate>20170901</enddate><creator>Ezemaduka, Anastasia N.</creator><creator>Wang, Yunbiao</creator><creator>Li, Xiujun</creator><general>Sciendo</general><general>The Society of Nematologists</general><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170901</creationdate><title>Expression of CeHSP17 Protein in Response to Heat Shock and Heavy Metal Ions</title><author>Ezemaduka, Anastasia N. ; Wang, Yunbiao ; Li, Xiujun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p321t-aa19a94e15b41ddc5558a304e48191fd2f6d3c4e17a54fa9bd575c1d964c861e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>biomarker</topic><topic>cadmium</topic><topic>CeHSP17</topic><topic>Free-living Nematodes</topic><topic>small heat shock proteins</topic><topic>zinc</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ezemaduka, Anastasia N.</creatorcontrib><creatorcontrib>Wang, Yunbiao</creatorcontrib><creatorcontrib>Li, Xiujun</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of nematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ezemaduka, Anastasia N.</au><au>Wang, Yunbiao</au><au>Li, Xiujun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Expression of CeHSP17 Protein in Response to Heat Shock and Heavy Metal Ions</atitle><jtitle>Journal of nematology</jtitle><addtitle>J Nematol</addtitle><date>2017-09-01</date><risdate>2017</risdate><volume>49</volume><issue>3</issue><spage>168</spage><epage>176</epage><pages>168-176</pages><issn>0022-300X</issn><eissn>2640-396X</eissn><abstract>Small heat shock proteins (sHSP) are ubiquitously found in all organisms, and with other heat shock proteins (HSP) such as HSP60, HSP70, HSP90, HSP100 made up the molecular chaperone family. They are involved in a wide range of biological processes which include among others cell resistance to biological and environmental stress conditions. In this study, we show by western blotting that CeHSP17, an sHSP of
, is significantly induced by high temperatures. Furthermore, in response to metal stress, the CeHSP17 protein expression was significantly induced by cadmium and zinc at high concentration of clearly cytotoxic range in wild-type
. Altogether, our results show the involvement of CeHSP17 protein in both environmental and biological stresses in
and establish for the first time the expression pattern of the CeHSP17 protein in response to thermal and metal stress conditions in
. The responses of CeHSP17 protein expression may serve as potential sensitive biomarker for metal-induced toxicity monitoring and environmental risk assessment.</abstract><cop>United States</cop><pub>Sciendo</pub><pmid>29062158</pmid><doi>10.21307/jofnem-2017-081</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of nematology, 2017-09, Vol.49 (3), p.168-176 |
| issn | 0022-300X 2640-396X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5644928 |
| source | PubMed Central |
| subjects | biomarker cadmium CeHSP17 Free-living Nematodes small heat shock proteins zinc |
| title | Expression of CeHSP17 Protein in Response to Heat Shock and Heavy Metal Ions |
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