Characteristics of symptomatic epilepsy in patients with brain tumours

• Published in: Biomolecules & biomedicine 2009-02, Vol.9 (1), p.81-84
• Main Authors: Alajbegović, Azra, Loga, Natasa, Alajbegović, Salem, Suljić, Enra
• Format: Article
• Language: English
• Subjects: Anticonvulsants - therapeutic use; Brain Neoplasms - complications; brain tumours; Carbamazepine - therapeutic use; Diazepam - therapeutic use; Epilepsy, Generalized - drug therapy; Epilepsy, Generalized - etiology; Epilepsy, Generalized - physiopathology; Female; Frontal Lobe - physiopathology; Humans; Male; Middle Aged; Paresis - etiology; Paresis - physiopathology; Parietal Lobe - physiopathology; Retrospective Studies; symptomatic epilepsy; Temporal Lobe - physiopathology
• ISSN: 1512-8601; 2831-0896; 1840-4812; 2831-090X
• DOI: 10.17305/bjbms.2009.2862

The aim of our work is to determine the total number, age, gender of the patients with the symptomatic epileptic seizures associated with brain tumours, tumour location, clinical signs and characteristics of epileptic seizures. We have analyzed medical documentation of the patients with brain tumours hospitalized at the Department of Neurology, University of Sarajevo Clinics Centre. This study is retrospective and includes time period from 1st January 2000 until 31st December 2005. During the observed period at the Department of Neurology in Sarajevo there were in total 9753 hospitalized patients, from which 101 (1,1%) patients with the brain tumour diagnosis. Average patient's age was 62,60 +/- 1,28 years. In one third of the patients (32%) were recorded epileptic seizures, without significant difference between genders. In case of symptomatic epilepsy, significantly more frequent locations of tumours were: in several lobes (28%), parietal lobe (25%), as well as frontal and temporal lobe (18,8% each), while there were no changes in cerebellum and brain stem (chi2 =7,174, p