Cost-Effectiveness of Fecal Microbiota Transplantation in the Treatment of Recurrent Clostridium Difficile Infection: A Literature Review

Clostridium difficile ( ) is a common cause of antibiotic--associated diarrhea (AAD), being responsible for 15--25% of all AAD cases. The purpose of this literature review is to determine the cost-effectiveness of fecal microbiota transplantation (FMT) and how it compares in this regard to the stand...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2017-08, Vol.9 (8), p.e1599-e1599
Main Authors: Arbel, Leor T, Hsu, Edmund, McNally, Keegan
Format: Article
Language:English
Subjects:
Antibiotics
Cost analysis
Endorsements
Feces
Gastroenterology
Hospital costs
Literature reviews
Medical research
Nosocomial infections
Older people
Patients
Preventive Medicine
Quality Improvement
Transplants & implants
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Summary:Clostridium difficile ( ) is a common cause of antibiotic--associated diarrhea (AAD), being responsible for 15--25% of all AAD cases. The purpose of this literature review is to determine the cost-effectiveness of fecal microbiota transplantation (FMT) and how it compares in this regard to the standard treatments of choice for recurrent C. difficile infection (CDI). The review of the literature along with the evaluation of three comparative cost effective analyses yielded findings consistent with the view that FMT is the most cost-effective option in treating recurrent CDI. There are some (but considerably less) data indicating that FMT may be a cost effective strategy in treating initial CDI, as well. The superior cost-effectiveness of FMT as compared to the preferred standards of treatment for recurrent CDI suggest FMT use should become more integrated in routine clinical practice. Increased utilization of FMTs would allow for better control of this increasingly problematic disease as well as lower costs associated with its management.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.1599