Effect of Aerobic Exercise on Cancer-related Fatigue

Fatigue is the most common side effect of cancer treatment with chemotherapy and/or radiation therapy, selected biologic response modifiers. The main purpose of this study is to evaluate the effects of aerobic exercise on cancer-related fatigue in patients of the solid tumor after chemotherapy and r...

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Bibliographic Details
Published in:Indian journal of palliative care 2017-10, Vol.23 (4), p.355-361
Main Authors: Patel, Jaivika Govindbhai, Bhise, Anjali R
Format: Article
Language:English
Subjects:
Aerobics
Anemia
Breast cancer
Cancer
Cancer therapies
Care and treatment
Causes of
Chemotherapy
Complications and side effects
Disease
Exercise
Fatigue
Fitness training programs
Health aspects
Immunology
Intervention
Metabolism
Original
Physical fitness
Quality of life
Radiation therapy
Sports medicine
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Summary:Fatigue is the most common side effect of cancer treatment with chemotherapy and/or radiation therapy, selected biologic response modifiers. The main purpose of this study is to evaluate the effects of aerobic exercise on cancer-related fatigue in patients of the solid tumor after chemotherapy and radiotherapy. After screening for cancer-related fatigue, 34 patients fulfilled the inclusive criteria and were assigned into two groups ( = 17 recruited in the intervention group and = 17 in control group). The intervention group received aerobic exercise program which included treadmill walking with low to moderate intensity (50%-70% of maximum heart rate), for 20-40 min/day for 5 days/week. Control group were taught stretching exercises of hamstrings, gastrocnemius, and soleus (to be done at home) and were encouraged to remain active. Outcome measures such as brief fatigue inventory (BFI), 6-min walk test, and functional assessment of cancer therapy-general (FACT-G) were taken at baseline and after 6-weeks. The data were analyzed using the Wilcoxon matched-pairs signed rank test for within group and Mann-Whitney U-test for between group comparisons. The results of this study showed that there was a significant reduction in cancer-related fatigue BFI score ( < 0.0001,), also there was significant improvement in the physical performance as in 6-min walk distance ( < 0.0001) and quality of life, FACT-G score ( = 0.0001). Aerobic exercise for 6 weeks has beneficial effects on cancer-related fatigue in patients with solid tumor after chemotherapy and/or radiotherapy.
ISSN:0973-1075
1998-3735
DOI:10.4103/IJPC.IJPC_65_17