Cardiac Autonomic Neuropathy: Why Should Cardiologists Care about That?

Background. Cardiac autonomic neuropathy (CAN) is a frequent but underdiagnosed complication of diabetes mellitus. It has a strong influence on various cardiac disorders including myocardial ischemia and infarction, hypertension, orthostatic hypotonia, heart failure, and arrhythmias. CAN can lead to...

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Bibliographic Details
Published in:Journal of diabetes research 2017-01, Vol.2017 (2017), p.1-9
Main Author: Bissinger, Andrzej
Format: Article
Language:English
Subjects:
Age
Atherosclerosis
Autonomic Nervous System Diseases - diagnosis
Blood pressure
Cardiovascular disease
Coronary vessels
Diabetes
Diabetes Complications - diagnosis
Diabetic Neuropathies - diagnosis
Diabetic neuropathy
Gene expression
Health risk assessment
Heart attacks
Heart Diseases - diagnosis
Heart failure
Heart rate
Humans
Hyperglycemia
Hypertension
Ischemia
Morbidity
Mortality
Nervous system
Pathogenesis
Population
Posture
Review
Womens health
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Summary:Background. Cardiac autonomic neuropathy (CAN) is a frequent but underdiagnosed complication of diabetes mellitus. It has a strong influence on various cardiac disorders including myocardial ischemia and infarction, hypertension, orthostatic hypotonia, heart failure, and arrhythmias. CAN can lead to severe morbidity and mortality and increase the risk of sudden cardiac death. Methods. This review article summarizes the latest evidence regarding the epidemiology, pathogenesis, influence on the cardiovascular system, and diagnostic methods for CAN. The methodology of this review involved analyzing available data from recent papers relevant to the topic of diabetic autonomic neuropathy and cardiac disorders. Conclusions. The early diagnosis of CAN can improve the prognosis and reduce adverse cardiac events. Methods based on heart rate variability enable the diagnosis of CAN even at a preclinical stage. These methods are simple and widely available for use in everyday clinical practice. According to the recently published Toronto Consensus Panel on Diabetic Neuropathy, all diabetic patients should be screened for CAN. Because diabetes mellitus often coexists with heart diseases and the most common methods used for diagnosis of CAN are based on ECG, not only diabetologists but also cardiologists should be responsible for diagnosis of CAN.
ISSN:2314-6745
2314-6753
DOI:10.1155/2017/5374176