Findings and differential diagnosis of fetal intracranial haemorrhage and fetal ischaemic brain injury: what is the role of fetal MRI?

Ventriculomegaly (VM) is a non-specific finding on fetal imaging. Identification of the specific aetiology is important, as it affects prognosis and may even change the course of current or future pregnancies. In this review, we will focus on the application of fetal MRI to demonstrate intracranial...

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Bibliographic Details
Published in:British journal of radiology 2017-02, Vol.90 (1070), p.20160253-20160253
Main Authors: Putbrese, Bryn, Kennedy, Anne
Format: Article
Language:English
Subjects:
Brain Injuries - diagnostic imaging
Brain Injuries - embryology
Diagnosis, Differential
Female
Fetal Diseases - diet therapy
Humans
Intracranial Hemorrhages - diet therapy
Intracranial Hemorrhages - embryology
Magnetic Resonance Imaging - methods
Other
Pregnancy
Prenatal Diagnosis - methods
Review
Sensitivity and Specificity
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Summary:Ventriculomegaly (VM) is a non-specific finding on fetal imaging. Identification of the specific aetiology is important, as it affects prognosis and may even change the course of current or future pregnancies. In this review, we will focus on the application of fetal MRI to demonstrate intracranial haemorrhage and ischaemic brain injury as opposed to other causes of VM. MRI is able to identify the specific aetiology of VM with much more sensitivity and specificity than ultrasound and should be considered whenever VM is identified on obstetric ultrasound. Advances in both fetal and neonatal MRI have the potential to shed further light on mechanisms of brain injury and the impact of chronic hypoxia; such information may guide future interventions.
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr.20160253