Effective method of measuring the radioactivity of [ 131I]‐capsule prior to radioiodine therapy with significant reduction of the radiation exposure to the medical staff

Radiation Protection in Radiology, Nuclear Medicine and Radio Oncology is of the utmost importance. Radioiodine therapy is a frequently used and effective method for the treatment of thyroid disease. Prior to each therapy the radioactivity of the [ 131I]‐capsule must be determined to prevent misadmi...

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Bibliographic Details
Published in:Journal of applied clinical medical physics 2016-07, Vol.17 (4), p.59-72
Main Authors: Lützen, Ulf, Zhao, Yi, Marx, Marlies, Imme, Thea, Assam, Isong, Siebert, Frank‐Andre, Culman, Juraj, Zuhayra, Maaz
Format: Article
Language:English
Subjects:
[ 131I]‐capsule measurement
Humans
Inhalation Exposure - analysis
Iodine Radioisotopes - analysis
Iodine Radioisotopes - therapeutic use
Medical Staff, Hospital
Radiation Dosage
radiation exposure
Radiation Exposure - analysis
Radiation Oncology Physics
radiation protection
Radiation Protection - standards
Radioactivity
radioiodine therapy
Radiometry - methods
Thyroid gland
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Summary:Radiation Protection in Radiology, Nuclear Medicine and Radio Oncology is of the utmost importance. Radioiodine therapy is a frequently used and effective method for the treatment of thyroid disease. Prior to each therapy the radioactivity of the [ 131I]‐capsule must be determined to prevent misadministration. This leads to a significant radiation exposure to the staff. We describe an alternative method, allowing a considerable reduction of the radiation exposure. Two [ 131I]‐capsules (A01=2818.5; A02=73.55.0 MBq) were measured multiple times in their own delivery lead containers — that is to say, [ 131I]‐capsules remain inside the containers during the measurements (shielded measurement) using a dose calibrator and a well‐type and a thyroid uptake probe. The results of the shielded measurements were correlated linearly with the [ 131I]‐capsules radioactivity to create calibration curves for the used devices. Additional radioactivity measurements of 50 [ 131I]‐capsules of different radioactivities were done to validate the shielded measuring method. The personal skin dose rate (HP(0.07)) was determined using calibrated thermo luminescent dosimeters. The determination coefficients for the calibration curves were R2>0.9980 for all devices. The relative uncertainty of the shielded measurement was
ISSN:1526-9914
1526-9914
DOI:10.1120/jacmp.v17i4.5942