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Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence
This study investigated a 51-year-old married man with a history of heroin dependence who underwent methadone maintenance treatment for 7 years. He received traditional Chinese medicine (TCM)-facilitated treatments and switched from methadone to buprenorphine/naloxone. Strong anxiety symptoms were o...
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Published in: | BMJ case reports 2017-11, Vol.2017, p.bcr-2017-220815 |
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description | This study investigated a 51-year-old married man with a history of heroin dependence who underwent methadone maintenance treatment for 7 years. He received traditional Chinese medicine (TCM)-facilitated treatments and switched from methadone to buprenorphine/naloxone. Strong anxiety symptoms were observed during the initial stage; therefore, we prescribed a combination of Chaihu-Shugan-San, Zhi Bai Di Huang and Chin-Gin-Kuan-Ming decoction as the major herbal synergic regimen to relieve the symptoms of opioid withdrawal, anxiety and insomnia. During the treatment course, no precipitating withdrawal syndromes were noted, and the subject was gradually relieved of his anxiety symptoms through continual TCM treatments. In conclusion, TCM is effective in facilitating the switch from methadone to buprenorphine/naloxone and relieving anxiety symptoms. Therefore, focus on TCM-facilitated treatments for heroin dependence should be increased. |
doi_str_mv | 10.1136/bcr-2017-220815 |
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He received traditional Chinese medicine (TCM)-facilitated treatments and switched from methadone to buprenorphine/naloxone. Strong anxiety symptoms were observed during the initial stage; therefore, we prescribed a combination of Chaihu-Shugan-San, Zhi Bai Di Huang and Chin-Gin-Kuan-Ming decoction as the major herbal synergic regimen to relieve the symptoms of opioid withdrawal, anxiety and insomnia. During the treatment course, no precipitating withdrawal syndromes were noted, and the subject was gradually relieved of his anxiety symptoms through continual TCM treatments. In conclusion, TCM is effective in facilitating the switch from methadone to buprenorphine/naloxone and relieving anxiety symptoms. Therefore, focus on TCM-facilitated treatments for heroin dependence should be increased.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2017-220815</identifier><identifier>PMID: 29127135</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Acquired immune deficiency syndrome ; AIDS ; Anxiety ; Anxiety - prevention & control ; Anxiety disorders ; Asia ; Buprenorphine, Naloxone Drug Combination - administration & dosage ; Case reports ; Chinese ; Chinese medicine ; Drug Substitution ; Drugs, Chinese Herbal - therapeutic use ; Heroin ; Humans ; Male ; Methadone ; Methadone - administration & dosage ; Middle Aged ; Narcotics ; Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation) ; Opiate Substitution Treatment ; Opioid-Related Disorders - drug therapy ; Opioid-Related Disorders - psychology</subject><ispartof>BMJ case reports, 2017-11, Vol.2017, p.bcr-2017-220815</ispartof><rights>BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>Copyright: 2017 © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b3715-ab464d9009de5bd7be3731ae5409be5bf26b7dbefb7f69f65d5ba65de209b1353</citedby><cites>FETCH-LOGICAL-b3715-ab464d9009de5bd7be3731ae5409be5bf26b7dbefb7f69f65d5ba65de209b1353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695423/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695423/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29127135$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yu, Kai-Chiang</creatorcontrib><creatorcontrib>Wei, Han-Ting</creatorcontrib><creatorcontrib>Yeh, Yuh-Hsiang</creatorcontrib><creatorcontrib>Hsu, Chung-Hua</creatorcontrib><title>Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>This study investigated a 51-year-old married man with a history of heroin dependence who underwent methadone maintenance treatment for 7 years. 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Therefore, focus on TCM-facilitated treatments for heroin dependence should be increased.</description><subject>Acquired immune deficiency syndrome</subject><subject>AIDS</subject><subject>Anxiety</subject><subject>Anxiety - prevention & control</subject><subject>Anxiety disorders</subject><subject>Asia</subject><subject>Buprenorphine, Naloxone Drug Combination - administration & dosage</subject><subject>Case reports</subject><subject>Chinese</subject><subject>Chinese medicine</subject><subject>Drug Substitution</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Heroin</subject><subject>Humans</subject><subject>Male</subject><subject>Methadone</subject><subject>Methadone - administration & dosage</subject><subject>Middle Aged</subject><subject>Narcotics</subject><subject>Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation)</subject><subject>Opiate Substitution Treatment</subject><subject>Opioid-Related Disorders - drug therapy</subject><subject>Opioid-Related Disorders - psychology</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><recordid>eNqFkk2PFCEQhjtG427WPXszJF6MSTt8NM30xcRM_Eo28bIm3gg01TNMGmiBXnf-lL9R2l43qxc5QEE99RYUVVXPCX5DCGs3uo81xUTUlOIt4Y-qcyK4qEWHvz1-YJ9VlykdcRmMNNuGPa3OaEeoIIyfVz-vozI22-DViHYH6yEBcmBsX8x6UL0dbVYZDMoRVHbgc0JOnVCE0cINIOVvLeQTSic35eASMnO0fo9MnPco_bC5PyzbIQZXdPNBmeAB5YD0PEXwIU5L0k1JH24XzxDimmqJCpMN1iADE3gDvodn1ZNBjQku79aL6uuH99e7T_XVl4-fd--uas0E4bXSTduYDuPOANdGaGCCEQW8wZ0uJwNttTAaBi2GthtabrhWZQZa_KUu7KJ6u-pOsy7V6MuzoxrlFK1T8SSDsvJvj7cHuQ83krcdbygrAq_uBGL4PkPK0tnUwzgqD2FOknQtowJ3ZFvQl_-gxzDHUpDfFOWFo6RQm5XqY0gpwnB_GYLl0g6ytINc2kGu7VAiXjx8wz3_5_ML8HoFtDv-V-0XGAnEzw</recordid><startdate>20171109</startdate><enddate>20171109</enddate><creator>Yu, Kai-Chiang</creator><creator>Wei, Han-Ting</creator><creator>Yeh, Yuh-Hsiang</creator><creator>Hsu, Chung-Hua</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20171109</creationdate><title>Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence</title><author>Yu, Kai-Chiang ; Wei, Han-Ting ; Yeh, Yuh-Hsiang ; Hsu, Chung-Hua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b3715-ab464d9009de5bd7be3731ae5409be5bf26b7dbefb7f69f65d5ba65de209b1353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Anxiety</topic><topic>Anxiety - prevention & control</topic><topic>Anxiety disorders</topic><topic>Asia</topic><topic>Buprenorphine, Naloxone Drug Combination - administration & dosage</topic><topic>Case reports</topic><topic>Chinese</topic><topic>Chinese medicine</topic><topic>Drug Substitution</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Heroin</topic><topic>Humans</topic><topic>Male</topic><topic>Methadone</topic><topic>Methadone - administration & dosage</topic><topic>Middle Aged</topic><topic>Narcotics</topic><topic>Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation)</topic><topic>Opiate Substitution Treatment</topic><topic>Opioid-Related Disorders - drug therapy</topic><topic>Opioid-Related Disorders - psychology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yu, Kai-Chiang</creatorcontrib><creatorcontrib>Wei, Han-Ting</creatorcontrib><creatorcontrib>Yeh, Yuh-Hsiang</creatorcontrib><creatorcontrib>Hsu, Chung-Hua</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yu, Kai-Chiang</au><au>Wei, Han-Ting</au><au>Yeh, Yuh-Hsiang</au><au>Hsu, Chung-Hua</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2017-11-09</date><risdate>2017</risdate><volume>2017</volume><spage>bcr-2017-220815</spage><pages>bcr-2017-220815-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>This study investigated a 51-year-old married man with a history of heroin dependence who underwent methadone maintenance treatment for 7 years. He received traditional Chinese medicine (TCM)-facilitated treatments and switched from methadone to buprenorphine/naloxone. Strong anxiety symptoms were observed during the initial stage; therefore, we prescribed a combination of Chaihu-Shugan-San, Zhi Bai Di Huang and Chin-Gin-Kuan-Ming decoction as the major herbal synergic regimen to relieve the symptoms of opioid withdrawal, anxiety and insomnia. During the treatment course, no precipitating withdrawal syndromes were noted, and the subject was gradually relieved of his anxiety symptoms through continual TCM treatments. In conclusion, TCM is effective in facilitating the switch from methadone to buprenorphine/naloxone and relieving anxiety symptoms. Therefore, focus on TCM-facilitated treatments for heroin dependence should be increased.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>29127135</pmid><doi>10.1136/bcr-2017-220815</doi><oa>free_for_read</oa></addata></record> |
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subjects | Acquired immune deficiency syndrome AIDS Anxiety Anxiety - prevention & control Anxiety disorders Asia Buprenorphine, Naloxone Drug Combination - administration & dosage Case reports Chinese Chinese medicine Drug Substitution Drugs, Chinese Herbal - therapeutic use Heroin Humans Male Methadone Methadone - administration & dosage Middle Aged Narcotics Novel Treatment (New Drug/Intervention Established Drug/Procedure in New Situation) Opiate Substitution Treatment Opioid-Related Disorders - drug therapy Opioid-Related Disorders - psychology |
title | Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence |
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