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Real time complete Stokes polarimetric imager based on a linear polarizer array camera for tissue polarimetric imaging

Tissue polarimetric imaging measures Mueller matrices of tissues or Stokes vectors of the emergent light from tissues (normally using incidence with a fixed polarization state) over a field of view, and has demonstrated utility in a number of surgical and diagnostic applications. Here we introduce a...

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Published in:Biomedical optics express 2017-11, Vol.8 (11), p.4933-4946
Main Authors: Qi, Ji, He, Chao, Elson, Daniel S
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Language:English
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creator Qi, Ji
He, Chao
Elson, Daniel S
description Tissue polarimetric imaging measures Mueller matrices of tissues or Stokes vectors of the emergent light from tissues (normally using incidence with a fixed polarization state) over a field of view, and has demonstrated utility in a number of surgical and diagnostic applications. Here we introduce a compact complete Stokes polarimetric imager that can work for multiple wavelength bands with a frame-rate suitable for real-time applications. The imager was validated with standard polarizing components, and then employed as a polarization state analyzer of a Mueller imaging polarimeter and a standalone Stokes imaging polarimeter respectively to image the process of dehydration of bovine tendon tissue. The results obtained in this work suggested that the polarization properties of the samples rich of collagen fibres can change with the degree of dehydration, and therefore, dehydration of the samples prepared for polarimetric imaging (e.g. polarimetric microscopy) should be carefully controlled.
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title Real time complete Stokes polarimetric imager based on a linear polarizer array camera for tissue polarimetric imaging
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