Ni-Catalyzed Enantioselective Conjunctive Cross-Coupling of 9-BBN Borates

Catalytic enantioselective conjunctive cross-coupling between 9-BBN borate complexes and aryl electrophiles can be accomplished with Ni salts in the presence of a chiral diamine ligand. The reactions furnish chiral 9-BBN derivatives in an enantioselective fashion and these are converted to chiral al...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2017-08, Vol.56 (39), p.11870-11874
Main Authors: Chierchia, Matteo, Law, Chunyin, Morken, James P.
Format: Article
Language:English
Online Access:Get full text
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Summary:Catalytic enantioselective conjunctive cross-coupling between 9-BBN borate complexes and aryl electrophiles can be accomplished with Ni salts in the presence of a chiral diamine ligand. The reactions furnish chiral 9-BBN derivatives in an enantioselective fashion and these are converted to chiral alcohols and amines, or engaged in other stereospecific C-C bond forming reactions. Conjunctive Coupling : Ni-Catalyzed conjunctive couplings furnish chiral 9-BBN derivatives in an enantioselective fashion and these are converted to chiral alcohols and amines, or they can be engaged in other stereospecific C-C bond forming reactions.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201706719