Relationship between Smoking and Acute Mountain Sickness: A Meta-Analysis of Observational Studies

Aims. Previous epidemiological investigations of the relationship between smoking and acute mountain sickness (AMS) risk yielded inconsistent findings. Therefore, a meta-analysis of observational studies was performed to determine whether smoking is related to the development of AMS. Methods. Search...

Full description

Saved in:
Bibliographic Details
Published in:BioMed research international 2017-01, Vol.2017 (2017), p.1-9
Main Authors: Ramos, Sergio Morchón, Santangelo, Fernando Agüero, Sánchez-Mascuñano, Alba, Masuet-Aumatell, Cristina, Ramon-Torrell, Josep Maria
Format: Article
Language:English
Subjects:
Altitude
Altitude sickness
Altitude Sickness - physiopathology
Bias
Biology
Carbon monoxide
Clinical trials
Confidence intervals
Edema
Epidemiology
Health aspects
Humans
Illnesses
Influence of altitude
Influència de l'altitud
Meta-analysis
Metaanàlisi
Mountain sickness
Mountains
Muntanyes
Observació (Mètode científic)
Observation (Scientific method)
Observational studies
Preventive medicine
Quality assessment
Review
Risk
Risk assessment
Risk factors
Smokers
Smoking
Smoking - adverse effects
Smoking - physiopathology
Studies
Tabac
Tobacco
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aims. Previous epidemiological investigations of the relationship between smoking and acute mountain sickness (AMS) risk yielded inconsistent findings. Therefore, a meta-analysis of observational studies was performed to determine whether smoking is related to the development of AMS. Methods. Searches were performed on PubMed, Scopus, Embase, and Web of Science for relevant studies that were published before November 2016 reporting smoking prevalence and AMS. Two evaluators independently selected studies, extracted data, and assessed study quality. The pooled relative risks (RRs) and 95% confidence intervals (CIs) were obtained using random-effects models. Subgroup analyses were performed according to the type of participant, altitude, and study design. Results. A total of 11 observational studies involving 7,106 participants, 2,408 of which had AMS, were eligible for inclusion in this meta-analysis. The summary RR for AMS comparing smokers to nonsmokers was 1.02 (95% CI: 0.83 to 1.26). Specific analyses for altitude, type of participant, and study design yielded similar results. There was significant heterogeneity for all studies (Q=37.43; P
ISSN:2314-6133
2314-6141
DOI:10.1155/2017/1409656