Reference intervals and allometric scaling of two-dimensional echocardiographic measurements in 150 healthy cats

The objective of the study was to evaluate the effects of body weight (BW), breed, and sex on two-dimensional (2D) echocardiographic measures, reference ranges, and prediction intervals using allometrically-scaled data of left atrial (LA) and left ventricular (LV) size and LV wall thickness in healt...

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Bibliographic Details
Published in:Journal of Veterinary Medical Science 2017, Vol.79(11), pp.1764-1771
Main Authors: KARSTEN, Schober, STEPHANIE, Savino, VEDAT, Yildiz
Format: Article
Language:English
Subjects:
Body weight
cardiology
Cardiomyopathy
cardiovascular system
cat
diagnosis
Echocardiography
Heart
Independent variables
Internal Medicine
Scaling
Septum
Sex
Two dimensional analysis
Ventricle
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Summary:The objective of the study was to evaluate the effects of body weight (BW), breed, and sex on two-dimensional (2D) echocardiographic measures, reference ranges, and prediction intervals using allometrically-scaled data of left atrial (LA) and left ventricular (LV) size and LV wall thickness in healthy cats. Study type was retrospective, observational, and clinical cohort. 150 healthy cats were enrolled and 2D echocardiograms analyzed. LA diameter, LV wall thickness, and LV dimension were quantified using three different imaging views. The effect of BW, breed, sex, age, and interaction (BW*sex) on echocardiographic variables was assessed using univariate and multivariate regression and linear mixed model analysis. Standard (using raw data) and allometrically scaled (Y=a × Mb) reference intervals and prediction intervals were determined. BW had a significant (P6 kg) and smaller (
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.17-0250