High plasma adenosine levels in overweight/obese pregnant women

We aim to investigate whether overweight/obese pregnant women have elevated plasma levels of adenosine associated with increased consumption of high-calorie food. Sixty women were included. They were divided into lean ( n  = 23 and n  = 12) or overweight/obese ( n  = 7 and n  = 18) non-pregnant and...

Full description

Saved in:
Bibliographic Details
Published in:Purinergic signalling 2017-12, Vol.13 (4), p.479-488
Main Authors: Badillo, Priscila, Salgado, Paola, Bravo, Patricia, Guevara, Katherine, Acurio, Jesenia, Gonzalez, Maria Angelica, Oyarzun, Carlos, San Martin, Rody, Escudero, Carlos
Format: Article
Language:English
Subjects:
Adenosine
Adenosine - blood
Adult
Biomedical and Life Sciences
Biomedicine
Body Mass Index
Body weight
Body weight gain
Cancer Research
Colorimetry
Cross-Sectional Studies
Diet
Female
Food consumption
High-performance liquid chromatography
Human Physiology
Humans
Neurosciences
Obesity
Obesity - blood
Original
Original Article
Overweight
Overweight - blood
Pharmacology/Toxicology
Plasma
Plasma levels
Polyunsaturated fatty acids
Pregnancy
Pregnancy Complications - blood
Proteins
Statistical analysis
Weight Gain
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We aim to investigate whether overweight/obese pregnant women have elevated plasma levels of adenosine associated with increased consumption of high-calorie food. Sixty women were included. They were divided into lean ( n  = 23 and n  = 12) or overweight/obese ( n  = 7 and n  = 18) non-pregnant and pregnant women, respectively. Clinical records and maternal blood samples were collected after informed consent. A self-reported dietary questionnaire was also completed. Plasma adenosine levels were determined with high-performance liquid chromatography. Biochemical parameters, including glucose, total protein, and lipid profile, were determined using standard colorimetric assays. Adenosine levels were higher in pregnant women than in non-pregnant women (18.7 ± 1.6 vs 10.8 ± 1.3 nM/μg protein, respectively, p  
ISSN:1573-9538
1573-9546
DOI:10.1007/s11302-017-9574-3