Fine-tuning type I IFN signaling： A new chapter in the IFN saga

Type I interferon （IFN） signaling is critical for intracellular antimicrobial programmes, affecting both innate and adaptive immune responses. The paper recently published in Cell demonstrates a new regulatory mechanism of the type I IFN signaling pathway by histone-lysine N-methyltransferase SETD2....

Full description

Saved in:
Bibliographic Details
Published in:Cell research 2017-12, Vol.27 (12), p.1407-1408
Main Authors: Yanai, Hideyuki, Taniguchi, Tadatsugu
Format: Article
Language:English
Subjects:
631/250/127/1212
631/250/516
631/80/86
692/420/755
Adaptive immunity
Antiviral Agents
Biomedical and Life Sciences
Cell Biology
Histone-Lysine N-Methyltransferase
Immune response
Interferon
Interferon Type I
Intracellular signalling
Life Sciences
Lysine
Methylation
Methyltransferase
N-Methyltransferase
Regulatory mechanisms (biology)
Research Highlight
Signal Transduction
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Type I interferon （IFN） signaling is critical for intracellular antimicrobial programmes, affecting both innate and adaptive immune responses. The paper recently published in Cell demonstrates a new regulatory mechanism of the type I IFN signaling pathway by histone-lysine N-methyltransferase SETD2.
ISSN:1001-0602
1748-7838
DOI:10.1038/cr.2017.118