Determination of an optimal organ set to implement deformations to support four‐dimensional dose calculations in radiation therapy planning

Surface‐based deformable image registration to generate a four‐dimensional (4D) dose calculation in radiation treatment planning requires the selection of a set of organ contours representing a basis set from which to generate anatomic deformation. The purpose of the present work was to determine th...

Full description

Saved in:
Bibliographic Details
Published in:Journal of applied clinical medical physics 2008-04, Vol.9 (2), p.69-82
Main Authors: Soofi, Wafa, Starkschall, George, Britton, Keith, Vedam, Sastry
Format: Article
Language:English
Subjects:
4D treatment planning
Accuracy
Algorithms
Biomechanical Phenomena
Datasets
deformable image registration
Deformation
Esophagus
Heart
Humans
Lung cancer
Lungs
Patients
Planning
Radiation Oncology Physics
Radiation therapy
Radiotherapy Planning, Computer-Assisted - methods
Respiration
respiratory motion
Spinal cord
Subtraction Technique
Thoracic Neoplasms - radiotherapy
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Surface‐based deformable image registration to generate a four‐dimensional (4D) dose calculation in radiation treatment planning requires the selection of a set of organ contours representing a basis set from which to generate anatomic deformation. The purpose of the present work was to determine the optimal set of organs needed to generate a basis set for deformation in treatment planning for thoracic tumors, such that the required computations are minimized, but that dose accuracy is high. Using retrospectively reviewed records and a deformable model algorithm in a research version of a commercial radiation treatment planning system, we calculated 4D dose distributions based on treatment plans for 10 patients with thoracic tumors. Various combinations of organs (total lungs, heart, spinal cord, external body surface) were used to generate the basis set used in the calculations for deformations. The external surface contour did not have a noticeable effect on the dose calculation. Total lung, heart, and spinal cord together provided an adequate set of deformation organs to generate accurate dose deformations. The magnitude of the calculated dose differences had no obvious relationship to tumor parameters, including site, histologic type, disease stage, extent of motion, or degree of centralization. PACS numbers: 87.55.D‐, 87.55.dk, 87.55.kh
ISSN:1526-9914
1526-9914
DOI:10.1120/jacmp.v9i2.2794