Trans-arterial radio-embolization: a new chance for patients with hepatocellular cancer to access liver transplantation, a world review

Liver transplantation (LT) for hepatocellular carcinoma (HCC) within the Milan criteria (MC) is nowadays a curative procedure. Yttrium-90 microspheres radioembolization (Y90-RE) has shown to be an effective and safe treatment of primary liver tumors. The aim of this work is to offer a view on the pu...

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Published in:Translational gastroenterology and hepatology 2017-11, Vol.2 (11), p.98-98
Main Authors: Levi Sandri, Giovanni Battista, Ettorre, Giuseppe Maria, Giannelli, Valerio, Colasanti, Marco, Sciuto, Rosa, Pizzi, Giuseppe, Cianni, Roberto, D'Offizi, Gianpiero, Antonini, Mario, Vennarecci, Giovanni, Lucatelli, Pierleone
Format: Article
Language:English
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Review
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Summary:Liver transplantation (LT) for hepatocellular carcinoma (HCC) within the Milan criteria (MC) is nowadays a curative procedure. Yttrium-90 microspheres radioembolization (Y90-RE) has shown to be an effective and safe treatment of primary liver tumors. The aim of this work is to offer a view on the publications which report on the use of Y90-RE as bridge or downstaging prior to LT. Twenty articles have been considered for this world review. About 178 LT in patients were treated with Y90-RE prior to LT. Most of patients had a downstaging strategy. In all series alpha-fetoproteins decreased between Y90-RE and LT. Therefore, Y90-RE may have an important role in the bridge and downstaging treatments.
ISSN:2415-1289
2415-1289
DOI:10.21037/tgh.2017.11.11