Association between maternal haemoglobin and stillbirth: a cohort study among a multi‐ethnic population in England

Summary The study objectives were to examine the association of maternal haemoglobin with stillbirth and perinatal death in a multi‐ethnic population in England. We conducted a retrospective cohort analysis using anonymised maternity data from 14 001 women with singleton pregnancies ≥24 weeks’ gesta...

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Bibliographic Details
Published in:British journal of haematology 2017-12, Vol.179 (5), p.829-837
Main Authors: Nair, Manisha, Churchill, David, Robinson, Susan, Nelson‐Piercy, Cathy, Stanworth, Simon J., Knight, Marian
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Anemia - epidemiology
Cohort Studies
England - epidemiology
Female
haemoglobin concentration
Hemoglobins - analysis
Humans
Infant, Newborn
maternal anaemia
Middle Aged
Perinatal Death
Pregnancy
Pregnancy Complications, Hematologic - epidemiology
Pregnancy Outcome
Research Paper
Retrospective Studies
Risk Factors
stillbirth
Stillbirth - epidemiology
Transfusion
Young Adult
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Summary:Summary The study objectives were to examine the association of maternal haemoglobin with stillbirth and perinatal death in a multi‐ethnic population in England. We conducted a retrospective cohort analysis using anonymised maternity data from 14 001 women with singleton pregnancies ≥24 weeks’ gestation giving birth between 2013 and 2015 in two hospitals ‐ the Royal Wolverhampton NHS Trust and Guy's and St Thomas’ NHS Foundation Trust. Multivariable logistic regression analyses were undertaken to analyse the associations between maternal haemoglobin at first visit and at 28 weeks with stillbirth and perinatal death, adjusting for 11 other risk factors. Results showed that 46% of the study population had anaemia (haemoglobin
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.14961