The importance of direct immunofluorescence in pemphigus herpetiformis diagnosis

Pemphigus herpetiformis is an autoimmune bullous disease, that combines clinical features of dermatitis herpetiformis and linear IgA bullous dermatosis and immunological characteristics of pemphigus, which makes this disease peculiar and this diagnosis rarely suspected in the first evaluation of the...

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Bibliographic Details
Published in:Anais brasileiros de dermatología 2017-01, Vol.92 (5 Suppl 1), p.145-147
Main Authors: de Faria, Paula Carolina Pessanha, Cruz, Camila Caberlon, Abulafia, Luna Azulay, Maceira, Juan Manuel Pineiro, Cassia, Flávia de Freire, Medeiros, Paula Mota
Format: Article
Language:English
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Case Report
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Summary:Pemphigus herpetiformis is an autoimmune bullous disease, that combines clinical features of dermatitis herpetiformis and linear IgA bullous dermatosis and immunological characteristics of pemphigus, which makes this disease peculiar and this diagnosis rarely suspected in the first evaluation of the patient. The reported case is of a patient with clinically bullous disease similar to dermatitis herpetiformis, whose multiple biopsies were inconclusive, and only after direct immunofluorescence with a pemphigus pattern (intraepidermal intercellular pattern) the confirmation of the diagnosis was possible.
ISSN:0365-0596
1806-4841
DOI:10.1590/abd1806-4841.20174510