Pulmonary metastasis from uterine leiomyosarcoma in a patient with limited cutaneous systemic scleroderma

A 51‐year‐old woman, who was diagnosed as having limited cutaneous systemic scleroderma, presented with pulmonary nodules incidentally detected in a chest radiograph. The patient had surgical biopsy of the nodules. In microscopic examination of the specimens, proliferation, mitotic activity, and cel...

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Bibliographic Details
Published in:Journal of general and family medicine 2017-12, Vol.18 (6), p.418-421
Main Authors: Okauchi, Shinichiro, Watanabe, Hiroko, Tamura, Tomohiro, Takayashiki, Norio, Iguchi, Kesato, Satoh, Hiroaki, Sato, Taiki, Sakata, Akiko, Noguchi, Masayuki
Format: Article
Language:English
Subjects:
Case Report
Case Reports
Gynecology
Hospitals
Infectious diseases
Laboratories
limited cutaneous systemic scleroderma
Lung cancer
Lungs
Medical imaging
Metastasis
Patients
pulmonary metastasis
Scleroderma
Thoracic surgery
Tomography
Tumors
uterine leiomyosarcoma
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Description
Summary:A 51‐year‐old woman, who was diagnosed as having limited cutaneous systemic scleroderma, presented with pulmonary nodules incidentally detected in a chest radiograph. The patient had surgical biopsy of the nodules. In microscopic examination of the specimens, proliferation, mitotic activity, and cellular anaplasia of spindle cells were present. Fluorodeoxyglucose‐positron emission tomography showed tumors in lungs as well as uterus. The diagnosis of the tumor was pulmonary metastases from uterine leiomyosarcoma. We should be on alert the possibility of developing malignant disease in patient with this autoimmune disease. If it is certain that there is metastasis, we believe that therapy for the primary lesion will be preceded by biopsy and surgery for the metastatic lesions.
ISSN:2189-7948
2189-6577
2189-7948
DOI:10.1002/jgf2.84