Increased Risk of the APOB rs11279109 Polymorphism for CHD among the Kuwaiti Population

Background. Coronary heart disease (CHD) is among the leading causes of death in Kuwait. This case-control study investigated the genetic association of APOB rs11279109 with CHD in Kuwaitis. Methods. The polymorphism was genotyped in 734 Kuwaiti samples by direct amplification. Statistical analysis...

Full description

Saved in:
Bibliographic Details
Published in:Disease markers 2017-01, Vol.2017 (2017), p.1-8
Main Authors: Al-Rashdan, Ibrahim, Al-Serri, Ahmad, Ismael, Fatma G., al-Bustan, Suzanne A.
Format: Article
Language:English
Subjects:
Apolipoprotein B-100 - genetics
Apolipoproteins
Body mass
Cardiovascular disease
Cardiovascular diseases
Coronary artery disease
Coronary Disease - genetics
Coronary heart disease
Diagnosis
Female
Genetic analysis
Genetic aspects
Genetic markers
Genotype & phenotype
Genotypes
Health aspects
Health risk assessment
Heart diseases
Humans
Hypercholesterolemia
Kuwait
Low density lipoprotein
Male
Mathematical models
Middle Aged
Minority & ethnic groups
Molecular modelling
Oxidation
Polymorphism
Polymorphism, Single Nucleotide
Population (statistical)
Risk
Risk factors
Smoking
Statistical analysis
Statistical methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background. Coronary heart disease (CHD) is among the leading causes of death in Kuwait. This case-control study investigated the genetic association of APOB rs11279109 with CHD in Kuwaitis. Methods. The polymorphism was genotyped in 734 Kuwaiti samples by direct amplification. Statistical analysis with genetic modeling was used to assess its association with CHD. Results. A statistically significant association (P
ISSN:0278-0240
1875-8630
DOI:10.1155/2017/6963437