Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China

We identified the genome sequences of two isolates. They were resistant to rifampin and isoniazid, as determined by the agar proportion method, but were susceptible to isoniazid, as determined by the DNA array method. The genome sequences showed that a deletion led to the false diagnosis of isoniazi...

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Bibliographic Details
Published in:Genome announcements (Washington, DC) DC), 2018-01, Vol.6 (1)
Main Authors: Chen, Zhenghong, Ou, Weizheng, Fan, Xiangyu, Cui, Guzhen, Wang, Qiong, Li, Qiang, Sun, Rong, Wu, Xiaojuan, Qin, Wan, Wang, Yan
Format: Article
Language:English
Subjects:
Deoxyribonucleic acid
DNA
Drug resistance
Genomes
Laboratories
Multidrug resistant organisms
Mutation
Prokaryotes
Public health
Tuberculosis
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Summary:We identified the genome sequences of two isolates. They were resistant to rifampin and isoniazid, as determined by the agar proportion method, but were susceptible to isoniazid, as determined by the DNA array method. The genome sequences showed that a deletion led to the false diagnosis of isoniazid resistance by DNA array.
ISSN:2169-8287
2169-8287
2576-098X
DOI:10.1128/genomeA.01257-17