Loading…
Effect of Gender on Treatment and Outcomes in Severe Aortic Stenosis
The aim of this study was to evaluate the effect of gender on operative rates and outcomes in men and women with severe aortic stenosis. An institutional echocardiographic database was used to identify all adult patients with severe aortic stenosis from 2004 through 2005. Only patients with class I...
Saved in:
| Published in: | The American journal of cardiology 2011-06, Vol.107 (11), p.1681-1686 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | |
| container_end_page | 1686 |
| container_issue | 11 |
| container_start_page | 1681 |
| container_title | The American journal of cardiology |
| container_volume | 107 |
| creator | Hartzell, Maryanne, MD Malhotra, Rajeev, MD Yared, Kibar, MD Rosenfield, Hannah R Walker, Jennifer D., MD Wood, Malissa J., MD |
| description | The aim of this study was to evaluate the effect of gender on operative rates and outcomes in men and women with severe aortic stenosis. An institutional echocardiographic database was used to identify all adult patients with severe aortic stenosis from 2004 through 2005. Only patients with class I indication for aortic valve replacement (AVR) during the period of follow-up were included in the study. Three hundred sixty-two patients were identified with severe aortic stenosis and class I indication for AVR (52% women). Overall operative rate for the cohort was 72%. In patients who underwent AVR, Kaplan–Meier survival rates were the same for men and women. Sixty-four percent of women versus 81% of men underwent AVR (p |
| doi_str_mv | 10.1016/j.amjcard.2011.01.059 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5758865</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0002914911004723</els_id><sourcerecordid>2367222111</sourcerecordid><originalsourceid>FETCH-LOGICAL-e377t-a486ab30dcf4f3bde5b2207a9a55e1912728a1f27ae5078b683c06a91c0cf0263</originalsourceid><addsrcrecordid>eNpdkV9rFDEUxYModlv9CEoQik-75iaTP_MilNpWodCHrc8hk7mjWWeSmsws9Nub4tqqEAjh_nLuuecS8gbYBhioD7uNm3be5X7DGcCG1SPbZ2QFRrdraEE8JyvGGF-30LRH5LiUXX0CSPWSHHFoGmaMXJFPF8OAfqZpoFcYe8w0RXqb0c0Txpm62NObZfZpwkJDpFvcY0Z6lvIcPN3OGFMJ5RV5Mbix4OvDfUK-Xl7cnn9eX99cfTk_u16j0Hpeu8Yo1wnW-6EZRNej7Dhn2rVOSqyWuebGwcC1Q8m06ZQRninXgmd-YFyJE_Lxt-7d0k3Y--owu9He5TC5fG-TC_bfSgzf7be0t1JLY5SsAu8PAjn9XLDMdgrF4zi6iGkp1ijdGFCCV_Ldf-QuLTnW6azRTHDJlKjQ27_9PBr5E28FTg-AK96NQ3bRh_LENbwBBeJpMKzp7QNm68cQQ_3yA--xPLYGW7hldvuw2Ie9AjDWaC7EL2iun64</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>870325063</pqid></control><display><type>article</type><title>Effect of Gender on Treatment and Outcomes in Severe Aortic Stenosis</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Hartzell, Maryanne, MD ; Malhotra, Rajeev, MD ; Yared, Kibar, MD ; Rosenfield, Hannah R ; Walker, Jennifer D., MD ; Wood, Malissa J., MD</creator><creatorcontrib>Hartzell, Maryanne, MD ; Malhotra, Rajeev, MD ; Yared, Kibar, MD ; Rosenfield, Hannah R ; Walker, Jennifer D., MD ; Wood, Malissa J., MD</creatorcontrib><description>The aim of this study was to evaluate the effect of gender on operative rates and outcomes in men and women with severe aortic stenosis. An institutional echocardiographic database was used to identify all adult patients with severe aortic stenosis from 2004 through 2005. Only patients with class I indication for aortic valve replacement (AVR) during the period of follow-up were included in the study. Three hundred sixty-two patients were identified with severe aortic stenosis and class I indication for AVR (52% women). Overall operative rate for the cohort was 72%. In patients who underwent AVR, Kaplan–Meier survival rates were the same for men and women. Sixty-four percent of women versus 81% of men underwent AVR (p <0.001). After adjusting for multiple covariates, women had a 2.1-fold lower odds of undergoing AVR compared to men (p = 0.02). After matching for age and Society of Thoracic Surgery risk score, women underwent AVR at a 19% lower relative rate compared to men (p = 0.03); when stratified by gender, there was no difference in reasons for not undergoing AVR. In conclusion, despite similar outcomes after surgery, women with severe aortic stenosis are less likely than men to undergo AVR.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2011.01.059</identifier><identifier>PMID: 21440885</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier</publisher><subject>Aged ; Aged, 80 and over ; Aortic Valve Stenosis - diagnostic imaging ; Aortic Valve Stenosis - surgery ; Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Cardiovascular ; Endocardial and cardiac valvular diseases ; Female ; Gender ; Heart ; Heart surgery ; Humans ; Male ; Medical sciences ; Middle Aged ; Risk Assessment ; Severity of Illness Index ; Sex Factors ; Studies ; Surgical outcomes ; Treatment Outcome ; Ultrasonic imaging ; Ultrasonography</subject><ispartof>The American journal of cardiology, 2011-06, Vol.107 (11), p.1681-1686</ispartof><rights>Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Sequoia S.A. Jun 1, 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24241613$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21440885$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hartzell, Maryanne, MD</creatorcontrib><creatorcontrib>Malhotra, Rajeev, MD</creatorcontrib><creatorcontrib>Yared, Kibar, MD</creatorcontrib><creatorcontrib>Rosenfield, Hannah R</creatorcontrib><creatorcontrib>Walker, Jennifer D., MD</creatorcontrib><creatorcontrib>Wood, Malissa J., MD</creatorcontrib><title>Effect of Gender on Treatment and Outcomes in Severe Aortic Stenosis</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>The aim of this study was to evaluate the effect of gender on operative rates and outcomes in men and women with severe aortic stenosis. An institutional echocardiographic database was used to identify all adult patients with severe aortic stenosis from 2004 through 2005. Only patients with class I indication for aortic valve replacement (AVR) during the period of follow-up were included in the study. Three hundred sixty-two patients were identified with severe aortic stenosis and class I indication for AVR (52% women). Overall operative rate for the cohort was 72%. In patients who underwent AVR, Kaplan–Meier survival rates were the same for men and women. Sixty-four percent of women versus 81% of men underwent AVR (p <0.001). After adjusting for multiple covariates, women had a 2.1-fold lower odds of undergoing AVR compared to men (p = 0.02). After matching for age and Society of Thoracic Surgery risk score, women underwent AVR at a 19% lower relative rate compared to men (p = 0.03); when stratified by gender, there was no difference in reasons for not undergoing AVR. In conclusion, despite similar outcomes after surgery, women with severe aortic stenosis are less likely than men to undergo AVR.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Valve Stenosis - diagnostic imaging</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Biological and medical sciences</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Endocardial and cardiac valvular diseases</subject><subject>Female</subject><subject>Gender</subject><subject>Heart</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Sex Factors</subject><subject>Studies</subject><subject>Surgical outcomes</subject><subject>Treatment Outcome</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonography</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNpdkV9rFDEUxYModlv9CEoQik-75iaTP_MilNpWodCHrc8hk7mjWWeSmsws9Nub4tqqEAjh_nLuuecS8gbYBhioD7uNm3be5X7DGcCG1SPbZ2QFRrdraEE8JyvGGF-30LRH5LiUXX0CSPWSHHFoGmaMXJFPF8OAfqZpoFcYe8w0RXqb0c0Txpm62NObZfZpwkJDpFvcY0Z6lvIcPN3OGFMJ5RV5Mbix4OvDfUK-Xl7cnn9eX99cfTk_u16j0Hpeu8Yo1wnW-6EZRNej7Dhn2rVOSqyWuebGwcC1Q8m06ZQRninXgmd-YFyJE_Lxt-7d0k3Y--owu9He5TC5fG-TC_bfSgzf7be0t1JLY5SsAu8PAjn9XLDMdgrF4zi6iGkp1ijdGFCCV_Ldf-QuLTnW6azRTHDJlKjQ27_9PBr5E28FTg-AK96NQ3bRh_LENbwBBeJpMKzp7QNm68cQQ_3yA--xPLYGW7hldvuw2Ie9AjDWaC7EL2iun64</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>Hartzell, Maryanne, MD</creator><creator>Malhotra, Rajeev, MD</creator><creator>Yared, Kibar, MD</creator><creator>Rosenfield, Hannah R</creator><creator>Walker, Jennifer D., MD</creator><creator>Wood, Malissa J., MD</creator><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110601</creationdate><title>Effect of Gender on Treatment and Outcomes in Severe Aortic Stenosis</title><author>Hartzell, Maryanne, MD ; Malhotra, Rajeev, MD ; Yared, Kibar, MD ; Rosenfield, Hannah R ; Walker, Jennifer D., MD ; Wood, Malissa J., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e377t-a486ab30dcf4f3bde5b2207a9a55e1912728a1f27ae5078b683c06a91c0cf0263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Valve Stenosis - diagnostic imaging</topic><topic>Aortic Valve Stenosis - surgery</topic><topic>Biological and medical sciences</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular</topic><topic>Endocardial and cardiac valvular diseases</topic><topic>Female</topic><topic>Gender</topic><topic>Heart</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Sex Factors</topic><topic>Studies</topic><topic>Surgical outcomes</topic><topic>Treatment Outcome</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hartzell, Maryanne, MD</creatorcontrib><creatorcontrib>Malhotra, Rajeev, MD</creatorcontrib><creatorcontrib>Yared, Kibar, MD</creatorcontrib><creatorcontrib>Rosenfield, Hannah R</creatorcontrib><creatorcontrib>Walker, Jennifer D., MD</creatorcontrib><creatorcontrib>Wood, Malissa J., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hartzell, Maryanne, MD</au><au>Malhotra, Rajeev, MD</au><au>Yared, Kibar, MD</au><au>Rosenfield, Hannah R</au><au>Walker, Jennifer D., MD</au><au>Wood, Malissa J., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Gender on Treatment and Outcomes in Severe Aortic Stenosis</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>107</volume><issue>11</issue><spage>1681</spage><epage>1686</epage><pages>1681-1686</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>The aim of this study was to evaluate the effect of gender on operative rates and outcomes in men and women with severe aortic stenosis. An institutional echocardiographic database was used to identify all adult patients with severe aortic stenosis from 2004 through 2005. Only patients with class I indication for aortic valve replacement (AVR) during the period of follow-up were included in the study. Three hundred sixty-two patients were identified with severe aortic stenosis and class I indication for AVR (52% women). Overall operative rate for the cohort was 72%. In patients who underwent AVR, Kaplan–Meier survival rates were the same for men and women. Sixty-four percent of women versus 81% of men underwent AVR (p <0.001). After adjusting for multiple covariates, women had a 2.1-fold lower odds of undergoing AVR compared to men (p = 0.02). After matching for age and Society of Thoracic Surgery risk score, women underwent AVR at a 19% lower relative rate compared to men (p = 0.03); when stratified by gender, there was no difference in reasons for not undergoing AVR. In conclusion, despite similar outcomes after surgery, women with severe aortic stenosis are less likely than men to undergo AVR.</abstract><cop>New York, NY</cop><pub>Elsevier</pub><pmid>21440885</pmid><doi>10.1016/j.amjcard.2011.01.059</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 2011-06, Vol.107 (11), p.1681-1686 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5758865 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Aged Aged, 80 and over Aortic Valve Stenosis - diagnostic imaging Aortic Valve Stenosis - surgery Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular Endocardial and cardiac valvular diseases Female Gender Heart Heart surgery Humans Male Medical sciences Middle Aged Risk Assessment Severity of Illness Index Sex Factors Studies Surgical outcomes Treatment Outcome Ultrasonic imaging Ultrasonography |
| title | Effect of Gender on Treatment and Outcomes in Severe Aortic Stenosis |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T05%3A54%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20Gender%20on%20Treatment%20and%20Outcomes%20in%20Severe%20Aortic%20Stenosis&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Hartzell,%20Maryanne,%20MD&rft.date=2011-06-01&rft.volume=107&rft.issue=11&rft.spage=1681&rft.epage=1686&rft.pages=1681-1686&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2011.01.059&rft_dat=%3Cproquest_pubme%3E2367222111%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-e377t-a486ab30dcf4f3bde5b2207a9a55e1912728a1f27ae5078b683c06a91c0cf0263%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=870325063&rft_id=info:pmid/21440885&rfr_iscdi=true |