145: THE PREVALENCE OF FATTY LIVER IN OVERWEIGHT AND OBESE CHILDREN COMPARED TO NORMAL CHILDREN

• Published in: BMJ open 2017-02, Vol.7 (Suppl 1), p.bmjopen-2016-015415.145
• Main Authors: Zare, Mostafa, Zhiani Asgharzade, A, Mostafavi, S, Abbasi, F, Karimi, M, Sobhani Shahmirzadi, M, Zarei, H, Gharib, MH
• Format: Article
• Language: English
• Subjects: Abstracts from the 5th International Society for Evidence-Based Healthcare Congress, Kish Island, Ira; Alcohol use; Body mass index; Children & youth; Liver diseases
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2016-015415.145

Background and aims:Nonalcoholic fatty liver disease is the most common cause of liver disease worldwide and is defined as a disorder of excess fat accumulation in the liver. This study aimed to determine the prevalence of fatty liver among overweight and obese children compared to normal children.Methods:This case-control study was conducted on 90 children ages 5 to 13. Children's Body Mass Index (BMI) was determined and the three groups obese (95% >BMI), over weight (85–95% BMI) and normal (5–85% BMI) divided. People in the study were matched for age and sex. Liver enzymes (ALT & AST) and lipid profile were measured and a radiologist who didn't know children's BMI examined them based on fatty liver sonographic parameters. And finally data analyzed using SPSS (Ver-18), ANOVA and Tukey's tests. Sometimes data distribution wasn't normal and Kruskal-Wallis test was used.Results:The prevalence of fatty liver was 23/3% in obese children that was higher compared with normal (16/7%) and over weight (16/7%) children. Based on the result of this study the prevalence of fatty liver wasn't significantly different between the sexes. AST was significantly higher in children with normal BMI (p