Myofibroblasts: Master of disguise

Myofibroblasts are the unique population of smooth muscle-like fibroblasts. These cells have a role in growth factors secretion, matrix deposition and degradation. Thereby, myofibroblast contributes in both human physiology and pathology. This review explains the myofibroblastic lesions, imperative...

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Bibliographic Details
Published in:Journal of oral and maxillofacial pathology : JOMFP 2017-09, Vol.21 (3), p.462-463
Main Authors: Bagalad, Bhavana S, Mohan Kumar, K P, Puneeth, H K
Format: Article
Language:English
Subjects:
Cell adhesion & migration
Cell differentiation
Collagen
Cytokines
Fibroblasts
Glycoproteins
Growth factors
Inflammation
Kinases
Metastasis
Morphology
Organogenesis
Pathology
Review
Secretion
Smooth muscle
Squamous cell carcinoma
Stem cells
Tumor necrosis factor-TNF
Tumorigenesis
Tumors
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Summary:Myofibroblasts are the unique population of smooth muscle-like fibroblasts. These cells have a role in growth factors secretion, matrix deposition and degradation. Thereby, myofibroblast contributes in both human physiology and pathology. This review explains the myofibroblastic lesions, imperative role of myofibroblasts in organogenesis, repair, regeneration, inflammation and tumorigenesis.
ISSN:0973-029X
1998-393X
DOI:10.4103/jomfp.JOMFP_146_15