Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

We undertook a genome-wide association study (GWAS) of parental longevity in European descent UK Biobank participants. For combined mothers' and fathers' attained age, 10 loci were associated (p

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Bibliographic Details
Published in:Aging (Albany, NY.) NY.), 2017-12, Vol.9 (12), p.2504-2520
Main Authors: Pilling, Luke C, Kuo, Chia-Ling, Sicinski, Kamil, Tamosauskaite, Jone, Kuchel, George A, Harries, Lorna W, Herd, Pamela, Wallace, Robert, Ferrucci, Luigi, Melzer, David
Format: Article
Language:English
Subjects:
Adult
Aged
Biological Specimen Banks
Female
Genome-Wide Association Study
Humans
Longevity - genetics
Male
Middle Aged
Multifactorial Inheritance
Parents
Research Paper
United Kingdom
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Summary:We undertook a genome-wide association study (GWAS) of parental longevity in European descent UK Biobank participants. For combined mothers' and fathers' attained age, 10 loci were associated (p
ISSN:1945-4589
1945-4589
DOI:10.18632/aging.101334