Neutrophil and Lymphocyte Counts as Clinical Markers for Stratifying Low-Risk Prostate Cancer

Micro-Abstract Appropriate patient selection for active surveillance is challenging. Our study of 217 patients demonstrated that the preoperative absolute neutrophil and lymphocyte counts were better predictors of aggressive oncologic features than were the neutrophil-to-lymphocyte ratio in the asse...

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Bibliographic Details
Published in:Clinical genitourinary cancer 2016-02, Vol.14 (1), p.e1-e8
Main Authors: Kwon, Young Suk, Han, Christopher Sejong, Yu, Ji Woong, Kim, Sinae, Modi, Parth, Davis, Rachel, Park, Ji Hae, Lee, Paul, Ha, Yun-Sok, Kim, Wun-Jae, Kim, Isaac Yi
Format: Article
Language:English
Subjects:
Active surveillance
Disease-Free Survival
Hematology, Oncology and Palliative Medicine
Humans
Kallikreins - blood
Kaplan-Meier Estimate
Lymphocyte Count
Male
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local - blood
Neoplasm Recurrence, Local - immunology
Neoplasm Recurrence, Local - mortality
Neutrophil-to-lymphocyte ratio
Neutrophils - immunology
Pathological outcome
Prostate cancer
Prostate-Specific Antigen - blood
Prostatic Neoplasms - blood
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - immunology
Prostatic Neoplasms - mortality
Radical prostatectomy
Urology
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Summary:Micro-Abstract Appropriate patient selection for active surveillance is challenging. Our study of 217 patients demonstrated that the preoperative absolute neutrophil and lymphocyte counts were better predictors of aggressive oncologic features than were the neutrophil-to-lymphocyte ratio in the assessment of low-risk prostate cancer patients. Our findings suggest that routine hematologic workup could be used to further stratify low-risk prostate cancer patients.
ISSN:1558-7673
1938-0682
DOI:10.1016/j.clgc.2015.07.018