Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report

Lateral retropharyngeal lymph node (LRPLN) is located between the internal carotid artery and the prevertebral muscles. Metastasis to the LRPLN is frequent in nasopharyngeal cancer, but is rare in oral cancer. The prognosis of patients with oral cancer with LRPLN metastasis is usually poor. The pres...

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Bibliographic Details
Published in:Molecular and clinical oncology 2018-01, Vol.8 (1), p.68-72
Main Authors: Yamazaki, Hiroshi, Sasaki, Masashi, Aoyama, Ken-Ichi, Suzuki, Takatsugu, Denda, Yuya, Uchibori, Masahiro, Nakanishi, Yasuhiro, Kojima, Rena, Ota, Yoshihide
Format: Article
Language:English
Subjects:
Cancer metastasis
Cancer therapies
Care and treatment
Carotid arteries
Case reports
Case studies
Chemotherapy
Complications and side effects
Development and progression
Dissection
Family medical history
Lymphatic diseases
Lymphatic system
Metastasis
Mouth
Mouth tumors
Oral cancer
Patients
Radiation therapy
Squamous cell carcinoma
Surgery
Veins & arteries
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Summary:Lateral retropharyngeal lymph node (LRPLN) is located between the internal carotid artery and the prevertebral muscles. Metastasis to the LRPLN is frequent in nasopharyngeal cancer, but is rare in oral cancer. The prognosis of patients with oral cancer with LRPLN metastasis is usually poor. The present study reported a patient with LRPLN metastasis from squamous cell carcinoma of the upper gingiva, who survived for >7 years. Docetaxel, cisplatin and fluorouracil (TPF) therapy was performed as induction chemotherapy and it was planned to subsequently conduct chemoradiotherapy or surgery. As the tumor only exhibited a transient response to TPF, surgery was selected. Postoperatively, only radiotherapy was performed and a favorable outcome was achieved.
ISSN:2049-9450
2049-9469
DOI:10.3892/mco.2017.1496