A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly

NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID...

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Bibliographic Details
Published in:Aging and disease 2018-02, Vol.9 (1), p.143-150
Main Authors: Wongrakpanich, Supakanya, Wongrakpanich, Amaraporn, Melhado, Katie, Rangaswami, Janani
Format: Article
Language:English
Subjects:
Dosage and administration
Elderly patients
Health aspects
Inflammation
Nonsteroidal anti-inflammatory agents
Review
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Summary:NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly.
ISSN:2152-5250
2152-5250
DOI:10.14336/AD.2017.0306