Incidental detection of asymptomatic brain metastases on 18F-fluoride positron emission tomography/computed tomography and 68Ga DOTANOC positron emission tomography/computed tomography in a patient with concomitant breast carcinoma and a pancreatic neuroendocrine tumor

A 54-year-old female treated for locally advanced ductal breast carcinoma was also diagnosed with a pancreatic neuroendocrine tumour. A staging 68 Ga DOTANOC positron emission tomography/computed tomography (PET/CT) demonstrated somatostatin receptor-positive foci within the brain parenchyma. A whol...

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Bibliographic Details
Published in:World journal of nuclear medicine 2018-01, Vol.17 (1), p.65-66
Main Authors: Brown, Ruth, Chuah, Phei, Panagiotidis, Emmanouil, Vinjamuri, Sobhan
Format: Article
Language:English
Subjects:
Brain
Brain cancer
Breast cancer
Calcification
Cancer metastasis
Carcinoma
Case Report
Computation
Computed tomography
Fluorides
Histology
Magnetic resonance imaging
Medical imaging
Metastasis
NMR
Nuclear magnetic resonance
Nuclear medicine
Pancreatic cancer
Positron emission
Quality
Tomography
Tracers (Biology)
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Summary:A 54-year-old female treated for locally advanced ductal breast carcinoma was also diagnosed with a pancreatic neuroendocrine tumour. A staging 68 Ga DOTANOC positron emission tomography/computed tomography (PET/CT) demonstrated somatostatin receptor-positive foci within the brain parenchyma. A whole body 18 F-fluoride PET/CT also demonstrated several foci of low-grade tracer uptake in the brain. Magnetic resonance imaging confirmed several cerebral and cerebellar metastases. This case highlights the need to be aware of each tumor's metastatic profile and the careful attention required for thoroughly evaluating imaging in the presence of multiple pathologies. Furthermore, such incidental findings can have significant treatment and prognostic implications.
ISSN:1450-1147
1607-3312
DOI:10.4103/wjnm.WJNM_10_17