Fatal respiratory distress syndrome due to coronavirus infection in a child with severe combined immunodeficiency

• Published in: Influenza and other respiratory viruses 2013-09, Vol.7 (5), p.634-636
• Main Authors: Szczawinska‐Poplonyk, Aleksandra, Jonczyk‐Potoczna, Katarzyna, Breborowicz, Anna, Bartkowska‐Sniatkowska, Alicja, Figlerowicz, Magdalena
• Format: Article
• Language: English
• Subjects: Adolescent; Children; Coronavirus; Coronavirus - genetics; Coronavirus - isolation & purification; Coronavirus - physiology; Coronavirus Infections - complications; Coronavirus Infections - virology; Female; Humans; Infant; Part 1; pneumonia; Respiratory Distress Syndrome, Newborn - diagnosis; Respiratory Distress Syndrome, Newborn - etiology; severe combined immunodeficiency; Severe Combined Immunodeficiency - complications; Short
• ISSN: 1750-2640; 1750-2659
• DOI: 10.1111/irv.12059

Please cite this paper as: Szczawinska‐Poplonyk et al. (2012) Fatal respiratory distress syndrome due to coronavirus infection in a child with severe combined immunodeficiency. Influenza and Other Respiratory Viruses DOI: 10.1111/irv.12059. Coronaviruses have been demonstrated to contribute substantially to respiratory tract infections among the child population. Though infected children commonly present mild upper airway symptoms, in high‐risk patients with underlying conditions, particularly in immunocompromised children these pathogens may lead to severe lung infection and extrapulmonary disorders. In this paper, we provide the first report of the case of a 15‐month‐old child with severe combined immunodeficiency and coronavirus HKU1‐related pneumonia with fatal respiratory distress syndrome.