Echocardiographic Evaluation of the Right Atrial Area Index in Dogs with Pulmonary Hypertension

Background Right atrial area (RAA) is a prognostic factor in human patients with pulmonary arterial hypertension (PAH). Reference intervals for RAA have been described in healthy dogs. Objectives To evaluate RAA indexed to the body surface area in dogs with PAH as an indicator of right atrial size,...

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Bibliographic Details
Published in:Journal of veterinary internal medicine 2018-01, Vol.32 (1), p.42-47
Main Authors: Vezzosi, T., Domenech, O., Iacona, M., Marchesotti, F., Zini, E., Venco, L., Tognetti, R.
Format: Article
Language:English
Subjects:
canine
congestive heart failure
right atrial enlargement
right atrial size
SMALL ANIMAL
tricuspid regurgitation
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Summary:Background Right atrial area (RAA) is a prognostic factor in human patients with pulmonary arterial hypertension (PAH). Reference intervals for RAA have been described in healthy dogs. Objectives To evaluate RAA indexed to the body surface area in dogs with PAH as an indicator of right atrial size, PAH severity and right‐sided congestive heart failure (R‐CHF). Animals A total of 119 client‐owned dogs, 48 dogs with PAH and 71 control dogs. Methods Prospective observational study. Pulmonary arterial hypertension was classified according to the tricuspid regurgitation pressure gradient (TRPG) as mild (36–50 mmHg), moderate (51–75 mmHg), or severe (>75 mmHg). The RAA index was calculated as the RAA divided by body surface area. Results The RAA index was higher in dogs with moderate PAH (13.3 cm2/m2; range, 3.4–24.7 cm2/m2) and severe PAH (12.1 cm2/m2; range, 5.4–21.8 cm2/m2) than in those with mild PAH (6.7 cm2/m2; range, 4.8–10.7 cm2/m2) or in controls (7.3 cm2/m2; range, 4.2–10.2 cm2/m2; P 
ISSN:0891-6640
1939-1676
DOI:10.1111/jvim.15035