Emergency Caesarean Section Saved Both an Anti-MuSK Antibody-positive Myasthenia Gravis Mother with Pregnancy-induced Hypertension and Her Premature Baby

We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 5 days of pregnancy, and who underwent an emergency caesarean section...

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Bibliographic Details
Published in:Internal Medicine 2017/12/15, Vol.56(24), pp.3361-3364
Main Authors: Takahashi, Yoshiaki, Yamashita, Toru, Morihara, Ryuta, Nakano, Yumiko, Sato, Kota, Takemoto, Mami, Hishikawa, Nozomi, Ohta, Yasuyuki, Hayata, Kei, Masuyama, Hisashi, Okamura, Tomoka, Washio, Yosuke, Abe, Koji
Format: Article
Language:English
Subjects:
anti-MuSK antibody
Case Report
emergency caesarean section
Hypertension
Internal medicine
Mechanical ventilation
Muscles
MUSK protein
Myasthenia
Myasthenia gravis
Neonates
Neuromuscular junctions
Pregnancy
pregnancy-induced hypertension
premature baby
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Summary:We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 5 days of pregnancy, and who underwent an emergency caesarean section (CS). Her MG symptoms gradually improved in the subsequent weeks. The premature baby with positive MuSK antibodies was successfully delivered, but the male baby required temporary artificial ventilation. However, his condition also gradually improved over time. The present case suggests that an emergency CS could rescue both the mother, who was in critical condition, and the prematurely born baby, even when suffering from acute respiratory insufficiency.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.8636-16