Whole-body magnetic resonance imaging for detection of skeletal metastases in children and young people with primary solid tumors - systematic review

Background Many solid neoplasms have a propensity for osteomedullary metastases of which detection is important for staging and subsequent treatment. Whole-body magnetic resonance imaging (WB-MRI) has been shown to accurately detect osteomedullary metastases in adults, but these findings cannot be u...

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Bibliographic Details
Published in:Pediatric radiology 2018-02, Vol.48 (2), p.241-252
Main Authors: Smets, A. M., Deurloo, E. E., Slager, T. J. E., Stoker, J., Bipat, S.
Format: Article
Language:English
Subjects:
Adolescents
Adults
Biocompatibility
Biomedical materials
Children
Diagnostic systems
Imaging
Imaging techniques
Literature reviews
Magnetic resonance imaging
Medicine
Medicine & Public Health
Metastases
Metastasis
Neoplasms
Neuroradiology
NMR
Nuclear magnetic resonance
Nuclear Medicine
Oncology
Original
Original Article
Patients
Pediatrics
Radiation
Radiology
Resonance
Sensitivity
Solid tumors
Tumors
Ultrasound
Young adults
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Summary:Background Many solid neoplasms have a propensity for osteomedullary metastases of which detection is important for staging and subsequent treatment. Whole-body magnetic resonance imaging (WB-MRI) has been shown to accurately detect osteomedullary metastases in adults, but these findings cannot be unconditionally extrapolated to staging of children with malignant solid tumors. Objective To conduct a literature review on the sensitivity of WB-MRI for detecting skeletal metastases in children with solid tumors. Materials and methods Searches in MEDLINE and EMBASE databases up to 15 May 2017 were performed to identify studies on the diagnostic value of WB-MRI. Inclusion criteria were children and adolescents (age
ISSN:0301-0449
1432-1998
DOI:10.1007/s00247-017-4013-8