Experimental use of an extracellular matrix graft in pterygium surgery

A 40-year-old man presented with a primary pterygium of the right eye and underwent pterygium excision using mitomycin C and placement of an extracellular matrix (ECM) adjuvant. As an adjuvant in pterygium surgery, ECM serves as a scaffold while promoting the growth of normal conjunctiva. Perioperat...

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Bibliographic Details
Published in:Digital journal of ophthalmology 2017, Vol.23 (4), p.15-108
Main Authors: Anderson, Erik W, Dwarakanathan, Suri, Haddadin, Ramez
Format: Article
Language:English
Subjects:
Adult
Case Report
Conjunctiva - surgery
Extracellular Matrix - transplantation
Eyelids - surgery
Follow-Up Studies
Humans
Male
Ophthalmologic Surgical Procedures - methods
Pterygium - surgery
Transplantation, Autologous
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Summary:A 40-year-old man presented with a primary pterygium of the right eye and underwent pterygium excision using mitomycin C and placement of an extracellular matrix (ECM) adjuvant. As an adjuvant in pterygium surgery, ECM serves as a scaffold while promoting the growth of normal conjunctiva. Perioperatively, the ECM graft was found to be easily manipulated on the surgical field. It attached to the scleral bed with fibrin glue without complication. Postoperatively, there was no inflammation or local tissue reaction to the porcine ECM graft. At the most recent follow-up examination, 6 months postoperatively, there were no signs of recurrence of the pterygium past the limbus. This is the first report describing the use of ECM as an adjuvant to pterygium excision.
ISSN:1542-8958
1542-8958
DOI:10.5693/djo.02.2017.11.001