Secondhand Smoke-Prevalent Polycyclic Aromatic Hydrocarbon Binary Mixture-Induced Specific Mitogenic and Pro-inflammatory Cell Signaling Events in Lung Epithelial Cells

Low molecular weight polycyclic aromatic hydrocarbons (LMW PAHs;

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Bibliographic Details
Published in:Toxicological sciences 2017-05, Vol.157 (1), p.156-171
Main Authors: Osgood, Ross S, Upham, Brad L, Bushel, Pierre R, Velmurugan, Kalpana, Xiong, Ka-Na, Bauer, Alison K
Format: Article
Language:English
Subjects:
Animals
Cell Communication - drug effects
Cell Line
Connexin 43 - metabolism
Dose-Response Relationship, Drug
Enzyme Activation
Epithelial Cells - drug effects
Epithelial Cells - metabolism
Gap Junctions - drug effects
Inflammation - metabolism
Lung - drug effects
Lung - metabolism
Lung - pathology
Mice
Mitogen-Activated Protein Kinases - metabolism
Mitogens - metabolism
Polycyclic Aromatic Hydrocarbons - toxicity
Polycyclic Aromatic Hydrocarbons in Secondhand Smoke
Signal Transduction - drug effects
Tobacco Smoke Pollution
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Description
Summary:Low molecular weight polycyclic aromatic hydrocarbons (LMW PAHs;
ISSN:1096-6080
1096-0929
DOI:10.1093/toxsci/kfx027