CRISPR/Cas system for yeast genome engineering: advances and applications

Abstract The methods based on the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system have quickly gained popularity for genome editing and transcriptional regulation in many organisms, including yeast. This review aims to provide a comprehensive overvie...

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Bibliographic Details
Published in:FEMS yeast research 2017-08, Vol.17 (5)
Main Authors: Stovicek, Vratislav, Holkenbrink, Carina, Borodina, Irina
Format: Article
Language:English
Subjects:
CRISPR
CRISPR-Cas Systems
Gene Editing - methods
Gene regulation
Genetics, Microbial - methods
Genome editing
Genomes
Metabolic Engineering - methods
Minireview
Saccharomyces cerevisiae - genetics
Transcription
Yeast
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Description
Summary:Abstract The methods based on the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system have quickly gained popularity for genome editing and transcriptional regulation in many organisms, including yeast. This review aims to provide a comprehensive overview of CRISPR application for different yeast species: from basic principles and genetic design to applications. A comprehensive review on application of CRISPR technology in yeast.
ISSN:1567-1356
1567-1364
DOI:10.1093/femsyr/fox030